870521-30-5

870521-30-5 - Names and Identifiers

Name	(6-Isopropoxypyridin-3-yl)boronic acid
Synonyms	2-ISOPROXYPYRIDINE-5-BORONIC ACID 6-Isoproxypyridine-3-boronic acid 6-Isopropoxypyridin-3-boronic acid 2-Isopropoxy-5-pyridineboronic acid 6-Isopropoxypyridine-3-boronic acid 2-Isopropoxypyridine-5-boronic acid (6-Isopropoxy-3-pyridyl)boronic acid 6-Isopropoxypyridin-3-Ylboronic Acid (6-Isopropoxypyridin-3-yl)boronic acid [6-(propan-2-yloxy)pyridin-3-yl]boronic acid
CAS	870521-30-5
InChI	InChI=1S/C8H12BNO3/c1-6(2)13-8-4-3-7(5-10-8)9(11)12/h3-6,11-12H,1-2H3

870521-30-5 - Physico-chemical Properties

Molecular Formula	C8H12BNO3
Molar Mass	181
Density	1.16
Boling Point	325.5±52.0 °C(Predicted)
Flash Point	150.656 °C
Water Solubility	Slightly soluble in water.
Appearance	Solid
pKa	7.08±0.18(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

870521-30-5 - Introduction

(6-Isopropoxypyridin-3-yl)boronic acid, also known as (6-isopropoxypyridin-3-yl) boronic acid, is an organoboron compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless or yellowish solid.
-Molecular formula: C10H15BNO3
-Molecular weight: 209.04g/mol
-melting point: about 150-152 ℃
-Solubility: Soluble in many organic solvents, such as methanol, ethanol and dichloromethane.

Use:
- (6-Isopropoxypyridin-3-yl)boronic acid is an important organic synthesis intermediate. It is widely used in C- N, C- O and C- C bond forming reactions, such as Suzuki-Miyaura cross coupling reaction, Stille reaction and Negishi reaction.
-It can be used to synthesize biologically active molecules, such as drugs and pesticides.
-can also be used as a coordination reagent and catalyst.

Preparation Method:
(6-Isopropoxypyridin-3-yl) The preparation method of boronic acid can be carried out by the following steps:
1.6-isopropoxy pyridine and boric acid reaction, in the appropriate solvent heating reaction.
2. After the reaction, the product is obtained by crystallization or solvent evaporation.

Safety Information:
- (6-Isopropoxypyridin-3-yl)boronic acid is a relatively safe compound under the conditions of correct use and storage.
-Avoid direct contact with skin and eyes during operation.
-When in use, use appropriate personal protective equipment, such as laboratory gloves and safety goggles.
-Further safety information and handling methods should refer to the safety data sheet of the compound.

Last Update：2024-04-09 02:00:48