9,10-Anthracenedione, 8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-
Aloe-emodin-8-O-beta-D-glucopyranoside
CAS: 33037-46-6
Molecular Formula: C21H20O10
9,10-Anthracenedione, 8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)- - Names and Identifiers
9,10-Anthracenedione, 8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)- - Physico-chemical Properties
| Molecular Formula | C21H20O10 |
| Molar Mass | 432.38 |
| Density | 1.673±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 236-237℃ |
| Boling Point | 829.9±65.0 °C(Predicted) |
| Solubility | Insuluble (3.5E-3 g/L) (25 °C) |
| Appearance | Yellow powder |
| Color | Dark Orange to Dark Brown |
| pKa | 6.48±0.20(Predicted) |
| Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Physical and Chemical Properties | Light yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Polygonum multiflorum and rhubarb. |
9,10-Anthracenedione, 8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)- - Risk and Safety
| HS Code | 29389090 |
9,10-Anthracenedione, 8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)- - Reference
| Reference Show more | 1. Chen Tinggui, Wei Yu Ru, Zhang Liwei. Identification of pancreatic lipase inhibitors in Polygonum cuspidatum by magnetic beads Immobilized enzyme and LC-MS/MS [J]. Natural product research and development, 2017(2). 2. Luo Yiyuan, Liu juanxiu, Wang Feng, etc. Simultaneous determination of 13 components in caulis polygoni multiflori by ultra performance liquid chromatography-tandem mass spectrometry [J]. Chinese Journal of Traditional Chinese Medicine, 2016. 3. Longfei Lin, Hongmei Lin, Miao Zhang, Boran Ni, Xingbin Yin, Changhai Qu, Jian Ni,A novel method to analyze Hematopoietic components in polygnum multiflorum using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectroscopy, Journal 4. Lin, Longfei, et al. "Hepatotoxicity and mechanism study of chrysophanol-8-O-glucoside in vitro." Biomedicine & Pharmacotherapy 120 (2019): 109531.https://doi.org/10.1016/j.biopha.2019.109531 5. Zhang, Miao, et al. "Interpretation the hepatotoxicity based on pharmacokinetics investigated through oral administrated different extraction parts of Polygonum multiflorum on rats." Frontiers in pharmacology 9 (2018): 505.https://doi.org/10.3389/fphar.201 6. Huang, Juan et al. "Chemical profiles and metabolite study of raw and processed Polygoni Multiflori Radix in rats by UPLC-LTQ-Orbitrap MSn spectrometry." Chinese journal of natural medicines 16.5 (2018): 375-400.https://doi.org/10.1016/S1875-5364(18)30070 7. Lin, Longfei, et al. "Characterization of the constituents in rat plasma after oral administration of radix polygoni multiflori extracts by ultra‐performance liquid chromatography/quadrupole time‐of‐flight mass spectrometry." Biomedical Chromatography 29.1 8. [IF=3.743] Longfei Lin et al."Hepatotoxicity and mechanism study of chrysophanol-8-O-glucoside in vitro."Biomed Pharmacother. 2019 Dec;120:109531 9. [IF=3.373] Wanning Chen et al."The composition differences between small black beans and big black beans from different habitats and its effects on the processing of Polygonum multiflorum."Phytochem Analysis. 2021 Sep;32(5):767-779 10. [IF=1.618] Tao Yi et al."Simultaneous Quantitation of Five Bioactive Ingredients in Raw and Processed Fallopia multiflora by Employing UHPLC-Q-TOF-MS."J Chromatogr Sci. 2019 Aug;57(7):618-624 11. [IF=5.645] Huilan Yue et al."Hypoglycemic ingredients identification of Rheum tanguticum Maxim. ex Balf. by UHPLC-triple-TOF-MS/MS and interrelationships between ingredients content and glycosidase inhibitory activities."Ind Crop Prod. 2022 Apr;178:114595 |
9,10-Anthracenedione, 8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)- - Reference Information
| Plant Source: | Aloe Vera |
| biological activity | Aloe-emodin-8-O-β-D-glucopyranoside is a compound isolated from Saussrurea lappa, is a mild human protein tyrosine phosphatase 1B (hPTP1B) inhibitor with an IC50 value of 26.6 μm. |
| Target | IC50:26.6 μm (hPTP1B) |
| Use | for content determination/identification/pharmacological experiments |
Last Update：2024-04-09 20:52:54
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Product Name: Aloe-emodin-8-O-beta-D-glucopyranoside Visit Supplier Webpage Request for quotationCAS: 33037-46-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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