97627-24-2 - Names and Identifiers
Name | N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea
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Synonyms | N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea Urea, N-(2-chloro-6-methylphenyl)-N'-4-pyridinyl-
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CAS | 97627-24-2
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97627-24-2 - Physico-chemical Properties
Molecular Formula | C13H12ClN3O
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Molar Mass | 261.71 |
Storage Condition | -20℃ |
In vivo study | Compound shows anticonvulsant activity at 30 mg/kg in the initial tests with no signs of ataxia until 300 mg/kg. The activity seen with 30 mg/kg 37 is still present 4 h postdose. Compound is effective against seizures induced by maximal electroshock but does not protect mice from clonic seizures produced by the convulsant pentylenetetrazol. The overall pharmacological profile suggests that Compound would be of therapeutic use in the treatment of generalized tonic-clonic and partial seizures. Compound is selected for clinical trials. |
97627-24-2 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
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1 mM | 3.821 ml | 19.105 ml | 38.211 ml |
5 mM | 0.764 ml | 3.821 ml | 7.642 ml |
10 mM | 0.382 ml | 1.911 ml | 3.821 ml |
5 mM | 0.076 ml | 0.382 ml | 0.764 ml |
Last Update:2024-01-02 23:10:35
97627-24-2 - Reference Information
biological activity | N-[(1R)-4-[(aminominomethyl) amino]-1-[[[(1R)-1-(4-hydroxyphenyl)ethyl]amino]carbonyl]butyl]-Alpha-phenylbenzenaceetamide is an anticonvulsant, there is potential to study extensive tonic and partial seizure clonic. |
Last Update:2024-04-09 19:05:17