AE 3-208

Name	ONO-AE3-208
Synonyms	AE 3-208 ONO AE3 208 ONO-AE3-208 4-(4-cyano-2-(2-(4-fluoronaphthalen-1-yl)propanamido)phenyl)butanoic acid 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]Benzenebutanoic acid 4-{4-Cyano-2-[2-(4-fluoro-naphthalen-1-yl)-propionylamino]-phenyl}-butyric acid Benzenebutanoic acid, 4-cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]-
CAS	402473-54-5

Molecular Formula	C24H21FN2O3
Molar Mass	404.43
Density	1.30
Boling Point	662.4±55.0 °C(Predicted)
Appearance	powder
Color	white to beige
pKa	4.69±0.10(Predicted)
Storage Condition	-20°C
In vitro study	ONO-AE3-208 surpresses the in vitro cell invasion and migration in a dose-dependent manner without affecting cell proliferation. ONO-AE3-208 abolisheS CTGF in the presence of the EET synthesis inhibitor MS-PPOH. Arachidonic acid (AA) causeS dose-dependent dilation of the attached Af-Art, and this effect is blocked by ONO-AE3-208.
In vivo study	ONO-AE3-208 surpresses the in vivo bone metastasis of PC3 cells in mice. The photon tumor burdens are significantly increased in a time-dependent manner in the control group in comparison with those in the ONO-AE3-208-treated group. The rate of metastasis formation is significantly higher in the former than in the latter. The median time of metastasis formation is 29 d in the ONO-AE3-208-treated animals as compared with 21 d in the controls.

Last Update：2024-01-02 23:10:35

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Product Name: ONO-AE3-208 Visit Supplier Webpage Request for quotation
CAS: 402473-54-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

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AE 3-208

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