AI3-02748

AI3-02748 - Names and Identifiers

Name	1-(4-Nitrophenyl)piperidine
Synonyms	AI3-02748 AURORA 2061 BUTTPARK 9657-87 4-CHLORO-2-AMINOPYRIMIDINE 1-(4-Nitrophenyl)piperidine 1-Piperidino-4-nitrobenzene N-(4-NITROPHENYL)PIPERIDINE 1-(4-NITROPHENYL)PIPERIDINE Piperidine, 1-(4-nitrophenyl)- 6-amino-1,3-dimethyl-5-[2-[[3-(4-methylphenyl)-4-oxo-2-quinazolinyl]thio]-1-oxoethyl]pyrimidine-2,4-dione 6-amino-1,3-dimethyl-5-({[3-(4-methylphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]sulfanyl}acetyl)pyrimidine-2,4(1H,3H)-dione
CAS	6574-15-8
EINECS	229-492-7
InChI	InChI=1/C23H21N5O4S/c1-13-8-10-14(11-9-13)28-20(30)15-6-4-5-7-16(15)25-22(28)33-12-17(29)18-19(24)26(2)23(32)27(3)21(18)31/h4-11H,12,24H2,1-3H3

AI3-02748 - Physico-chemical Properties

Molecular Formula	C11H14N2O2
Molar Mass	206.24
Density	1.188±0.06 g/cm3(Predicted)
Melting Point	104-106°C
Boling Point	363.5±25.0 °C(Predicted)
Flash Point	346.5°C
Vapor Presure	9.68E-17mmHg at 25°C
pKa	1.92±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.706
MDL	MFCD00023662

AI3-02748 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S22 - Do not breathe dust. S36 - Wear suitable protective clothing.

AI3-02748 - Introduction

1-(4-Nitrophenyl)piperidine is an organic compound with the chemical formula C11H14N2O2. It is a white crystalline solid with a structure similar to benzene and piperidine rings.

The primary use of 1-(4-Nitrophenyl)piperidine is as a pharmaceutical intermediate. It can be used to synthesize various drugs, such as anticancer drugs, antipsychotic drugs, etc. In addition, it can also be used as a catalyst and reagent in organic synthesis reactions.

The preparation of 1-(4-Nitrophenyl)piperidine is usually carried out by the following steps: first, 1-(4-Nitrophenyl)piperidine hydrochloride is prepared by reacting the corresponding piperidinamine and nitric acid; then, the hydrochloride is converted into 1-(4-Nitrophenyl)piperidine by neutralization reaction under basic conditions.

Regarding safety information, 1-(4-Nitrophenyl)piperidine should be handled with care to avoid direct contact with skin, eyes and respiratory tract. It may be toxic to humans and may be mutagenic and carcinogenic. During use, protective equipment should be used to ensure operation in a well-ventilated place and to comply with relevant safety operating procedures.

Last Update：2024-04-09 21:01:54