Name | 2-hydroxy-3-methylbutyric acid |
Synonyms | AKOS 239-06 2-HYDROXYISOVALERIC ACID A-HYDROXYISOVALERIC ACID ALPHA-HYDROXYISOVALERIC ACID 2-hydroxy-3-methylbutyric acid 2-HYDROXY-3-METHYLBUTYRIC ACID (2S)-2-hydroxy-3-methylbutanoic acid calcium bis[(2S)-2-hydroxy-3-methylbutanoate] |
CAS | 4026-18-0 |
EINECS | 223-697-5 |
InChI | InChI=1/2C5H10O3.Ca/c2*1-3(2)4(6)5(7)8;/h2*3-4,6H,1-2H3,(H,7,8);/q;;+2/p-2/t2*4-;/m00./s1 |
Molecular Formula | C5H10O3 |
Molar Mass | 118.13 |
Density | 1.136±0.06 g/cm3(Predicted) |
Melting Point | 86-87 °C (lit.) |
Boling Point | 120-125 °C(Press: 17 Torr) |
Flash Point | 111.8°C |
Solubility | Soluble in dimethyl sulfoxide and methanol. |
Vapor Presure | 0.00793mmHg at 25°C |
Appearance | Solid |
Color | White |
pKa | 3.87±0.16(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 3-10 |
Biological activity | 2-Hydroxy-3-methylbutanoic acid (3-Methyl-2-hydroxybutyric acid, 2-Hydroxyisopentanoic acid, 2-Oxyisovalic acid) is a metabolite, in patients with phenylketonuria, methylmalonic acidemia, propionic acidemia, ketothiolase deficiency, isovaleric acidemia, polycarboxylase deficiency, glutaric acidemia or ornithyltransferase deficiency Found in the urine of patients. |