action | LL-37 also play an immune regulatory role by chemotaxis of immune cells, regulating the secretion of inflammatory promoting factors/inhibiting factors, coordinating natural immunity and acquired immunity and other functions. LL-37 can also act on vascular endothelial cells and epithelial cells to stimulate angiogenesis and promote injury repair. In addition, uncontrolled regulation of LL-37 expression can also cause many diseases. For example, in psoriasis, the increase in LL-37 expression may promote autoimmune response. |