ASC J9

ASC J9 - Names and Identifiers

Name	ASC J9
Synonyms	ASC J9 ASC-J9 CS-636 GO-Y025 (1E,4E,6E) DIMETHYLCURCUMIN ASC-J9 (GO-Y025, Dimethylcurcumin) 1,7-Bis-(3,4-dimethoxy-phenyl)-5-hydroxy-hepta-1,4,6-trien-3-one (1E,4E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-5-hydroxy-1,4,6-heptatrien-3-one (1E,4E,6E)-1,7-Bis(3,4-diMethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one (1E,4E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-5-hydroxy-1,4,6-heptatrien-3-one ASC-J9
CAS	917813-54-8
EINECS	1533716-785-6

ASC J9 - Physico-chemical Properties

Molecular Formula	C23H24O6
Molar Mass	396.43
Density	1.191
Melting Point	129-130℃
Boling Point	588.6±50.0 °C(Predicted)
pKa	8.34±0.60(Predicted)
Storage Condition	2-8°C

ASC J9 - Introduction

(ASC J9(ASC J9) is an organic compound, also known as J9.

Nature:
ASC J9 is a yellow crystal with high solubility. It is stable at room temperature, but decomposes at high temperatures.

Use:
ASC J9 is a lipid (fatty acid metabolism) receptor agonist with anti-inflammatory, anti-tumor and anti-hepatic fibrosis activities. It is widely used in the study of chronic kidney disease, autoimmune diseases and cancer and other related fields.

Method:
ASC J9 can be prepared by chemical synthesis. A specific preparation method includes reacting 3,4-dimethoxyphenyl bromoheptatrienone with 4-ethylphenyl boronic acid, followed by reduction, acylation and hydroxyketonation.

Safety Information:
ASC J9 is relatively safe when used and stored correctly, but it is still a toxic compound. Wear appropriate protective equipment such as lab gloves, goggles and protective clothing during operation. In addition, it should be operated in a well-ventilated area and avoid contact with skin, eyes and mucous membranes. If exposed, rinse immediately with plenty of water and seek medical help. During storage, keep away from ignition and flammable materials, and keep sealed.

Last Update：2024-04-09 20:52:54