AVL-3288 (CCMI)
[N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide
CAS: 917837-54-8
Molecular Formula: C19H15Cl2N3O2
AVL-3288 (CCMI) - Names and Identifiers
AVL-3288 (CCMI) - Physico-chemical Properties
| Molecular Formula | C19H15Cl2N3O2 |
| Molar Mass | 388.25 |
| Density | 1.412±0.06 g/cm3(Predicted) |
| Boling Point | 605.4±55.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Very Slightly) |
| Appearance | Solid |
| Color | Off-White to Pale Yellow |
| pKa | 10.37±0.70(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
| In vitro study | CCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. |
AVL-3288 (CCMI) - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.576 ml | 12.878 ml | 25.757 ml |
| 5 mM | 0.515 ml | 2.576 ml | 5.151 ml |
| 10 mM | 0.258 ml | 1.288 ml | 2.576 ml |
| 5 mM | 0.052 ml | 0.258 ml | 0.515 ml |
Last Update：2024-01-02 23:10:35
AVL-3288 (CCMI) - Reference Information
| biological activity | CCMI is an effective and selective α7 nAChR forward allosteric regulator, which does not bind to α7 nAChR through positive binding sites and activate it, and can effectively positively regulate the current induced by agonists on α7 nAChR. CCMI has potential efficacy in neurological cognitive disorders. |
| Target | α7 nAChR |
Last Update：2024-04-09 21:54:55
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Spot supply
Product Name: [N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide Visit Supplier Webpage Request for quotationCAS: 917837-54-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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