Acetamide, 2-chloro-N-(2,4,5-trifluorophenyl)-
2-Chloro-N-(2,4,5-trifluorophenyl)acetamide
CAS: 885267-45-8
Molecular Formula: C8H5ClF3NO
Acetamide, 2-chloro-N-(2,4,5-trifluorophenyl)- - Names and Identifiers
Acetamide, 2-chloro-N-(2,4,5-trifluorophenyl)- - Physico-chemical Properties
| Molecular Formula | C8H5ClF3NO |
| Molar Mass | 223.58 |
| Melting Point | 111.5-112.5 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD00077477 |
Acetamide, 2-chloro-N-(2,4,5-trifluorophenyl)- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
Acetamide, 2-chloro-N-(2,4,5-trifluorophenyl)- - Introduction
2-Chloro-N-(2,4,5-trifluorophenyl)acetamide (2-chloro-N-(2,4,5-trifluorophenyl)acetamide) is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless or yellowish crystal
-Molecular formula: C9H6ClF3NO
-Molecular weight: 251.59g/mol
-Melting point: 80-85 degrees Celsius
-Boiling point: 258 degrees Celsius
-Solubility: Soluble in organic solvents, such as ethanol, dimethylformamide, etc.
Use:
2-Chloro-N-(2,4,5-trifluorophenyl)acetamide are mainly used as chemical reagents and intermediates, and have important applications in the synthesis of pesticides, pharmaceuticals and dyes.
Preparation Method:
2-Chloro-N-(2,4,5-trifluorophenyl)acetamide can be synthesized by the following steps:
1.2,4,5-trifluorobenzoic acid reacts with sodium hypochlorite to generate 2,4,5-trifluorophenyl hypochlorite. (Reaction conditions: chlorine gas, room temperature reaction)
2. treating 2,4, 5-trifluorophenylhypochlorous acid with acetic anhydride to generate 2,4, 5-trifluorophenylacetic acid. (Reaction conditions: heating at an appropriate temperature under alkaline conditions)
3.2,4, 5-trifluorophenylacetic acid is reacted with chloroacetic acid to generate 2-Chloro-N-(2,4,5-trifluorophenyl)acetamide. (Reaction conditions: appropriate temperature, appropriate time)
Safety Information:
2-Chloro-N-(2,4,5-trifluorophenyl)acetamide should be stored in a dry, well-ventilated place. Appropriate protective measures, including wearing goggles and gloves, are required when handling and touching the compound. The compound may cause irritation and damage to the eyes, skin and respiratory tract. Avoid inhaling its dust or solution. In case of accidental contact or inhalation, wash immediately with plenty of water and seek medical help.
Nature:
-Appearance: colorless or yellowish crystal
-Molecular formula: C9H6ClF3NO
-Molecular weight: 251.59g/mol
-Melting point: 80-85 degrees Celsius
-Boiling point: 258 degrees Celsius
-Solubility: Soluble in organic solvents, such as ethanol, dimethylformamide, etc.
Use:
2-Chloro-N-(2,4,5-trifluorophenyl)acetamide are mainly used as chemical reagents and intermediates, and have important applications in the synthesis of pesticides, pharmaceuticals and dyes.
Preparation Method:
2-Chloro-N-(2,4,5-trifluorophenyl)acetamide can be synthesized by the following steps:
1.2,4,5-trifluorobenzoic acid reacts with sodium hypochlorite to generate 2,4,5-trifluorophenyl hypochlorite. (Reaction conditions: chlorine gas, room temperature reaction)
2. treating 2,4, 5-trifluorophenylhypochlorous acid with acetic anhydride to generate 2,4, 5-trifluorophenylacetic acid. (Reaction conditions: heating at an appropriate temperature under alkaline conditions)
3.2,4, 5-trifluorophenylacetic acid is reacted with chloroacetic acid to generate 2-Chloro-N-(2,4,5-trifluorophenyl)acetamide. (Reaction conditions: appropriate temperature, appropriate time)
Safety Information:
2-Chloro-N-(2,4,5-trifluorophenyl)acetamide should be stored in a dry, well-ventilated place. Appropriate protective measures, including wearing goggles and gloves, are required when handling and touching the compound. The compound may cause irritation and damage to the eyes, skin and respiratory tract. Avoid inhaling its dust or solution. In case of accidental contact or inhalation, wash immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:18:09
