Adipoyl chloride
Adipoyl chloride
CAS: 111-50-2
Molecular Formula: C6H8Cl2O2
Adipoyl chloride - Names and Identifiers
| Name | Adipoyl chloride |
| Synonyms | adipoyl Hexyl Dichlroide Adipoyl chloride Adipyl dichloride Adipic dichloride adipoyl dichloride Adipic acid dichloride hexanedioyl dichloride Hexanedioic acid dichloride 1,4-Bis(Chlorocarbonyl)butane 1,4-Butanedicarbonyl chloride~Hexanedioyl dichloride |
| CAS | 111-50-2 |
| EINECS | 203-876-4 |
| InChI | InChI=1/C6H8Cl2O2/c7-5(9)3-1-2-4-6(8)10/h1-4H2 |
Adipoyl chloride - Physico-chemical Properties
| Molecular Formula | C6H8Cl2O2 |
| Molar Mass | 183.03 |
| Density | 1.259g/mLat 25°C(lit.) |
| Melting Point | 262-264 °C |
| Boling Point | 105-107°C2mm Hg(lit.) |
| Flash Point | >230°F |
| Water Solubility | reacts |
| Vapor Presure | 0.00557mmHg at 25°C |
| Appearance | Liquid |
| Color | Clear brown |
| BRN | 507709 |
| Storage Condition | Store below +30°C. |
| Stability | Stability Reacts violently with water to form hydrochloric acid. Incompatible with water, alcohols, bases, oxidizing agents. Protect from moisture. |
| Sensitive | Moisture Sensitive |
| Refractive Index | n20/D 1.471(lit.) |
| Physical and Chemical Properties | Colorless or light yellow liquid. Boiling point 126(1.60kPa),105-107 ℃(0.27kPa), relative density 0.963, refractive index 1.4263, flash point 50 ℃. Can be miscible with ether and benzene, water and alcohol decomposition. |
Adipoyl chloride - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R34 - Causes burns R29 - Contact with water liberates toxic gas R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R14 - Reacts violently with water |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S8 - Keep container dry. |
| UN IDs | UN 3265 8/PG 2 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| TSCA | Yes |
| HS Code | 29171900 |
| Hazard Class | 8 |
| Packing Group | II |
Adipoyl chloride - Nature
Open Data Verified Data
colorless or light yellow liquid. The relative density was 0.963. Boiling point 126 ℃(1. 6kPa). Decomposition in water and alcohol. Refractive index 4263. Flash point 50 °c.
Last Update：2024-01-02 23:10:35
Adipoyl chloride - Preparation Method
Open Data Verified Data
adipic acid was used as a raw material, and thionyl chloride was used for chlorination at 90-95 ° C. To obtain a crude product, and the reaction product was refluxed and distilled under reduced pressure to remove the remaining thionyl chloride, thereby obtaining a finished adipyl chloride.
Last Update：2022-01-01 10:32:29
Adipoyl chloride - Use
Open Data Verified Data
organic intermediates. It is used in medicine to synthesize bile acid.
Last Update：2022-01-01 10:32:28
Adipoyl chloride - Safety
Open Data Verified Data
- This product is toxic. There is a strong corrosive, water absorption, easy to decompose, produce hydrogen chloride gas. Operators should wear protective equipment, equipment should be sealed to prevent leakage. The workshop should be well ventilated.
- glass bottle packaging, should be waterproof, sunscreen, sealed. Transport according to the regulations of toxic chemicals.
Last Update：2022-01-01 10:32:29
Adipoyl chloride - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Use | organic intermediates. It is used in medicine to synthesize bile acid. |
| production method | reaction between adipic acid and thionyl chloride: put adipic acid and thionyl chloride into a reaction Pan, reflux and chloride at 90-95 ℃ for 5H, the residual thionyl chloride was removed under reduced pressure to obtain the final product. Raw material consumption quota: Adipic acid 830kg/t, thionyl chloride 1660kg/t. |
Last Update：2024-04-10 22:29:15
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CAS: 111-50-2
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Product Name: Adipoyl chloride Request for quotation
CAS: 111-50-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
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CAS: 111-50-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
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