Afatinib Impurity 102
6-nitroquinazolin-4(1H)-one
CAS: 6943-17-5
Molecular Formula: C8H5N3O3
Afatinib Impurity 102 - Names and Identifiers
Afatinib Impurity 102 - Physico-chemical Properties
| Molecular Formula | C8H5N3O3 |
| Molar Mass | 191.14 |
| Density | 1?+-.0.1 g/cm3(Predicted) |
| Melting Point | 286-287 °C |
| Boling Point | 407.0±47.0 °C(Predicted) |
| Flash Point | 199.9°C |
| Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| Vapor Presure | 7.81E-07mmHg at 25°C |
| Appearance | Solid |
| Color | Yellow |
| pKa | -1.01±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.739 |
Afatinib Impurity 102 - Risk and Safety
| Hazard Class | IRRITANT |
Afatinib Impurity 102 - Introduction
6-Nitroquinazolin-4 (1H)-one, chemical formula C8H4N4O3, is an organic compound. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
-6-Nitroquinazolin-4 (1H)-one is a yellow to orange solid.
-It has a high melting point and thermal stability.
-Almost insoluble in water at room temperature, but soluble in some organic solvents such as chloroform, dichloromethane and dimethyl sulfoxide.
Use:
-6-Nitroquinazolin-4 (1H)-one is widely used in the field of organic synthesis.
-It can be used as a pharmaceutical intermediate for the synthesis of various biologically active compounds.
-In addition, it can also be used for the preparation of dyes, pigments and photosensitive materials.
Preparation Method:
- 6-nitroquinazolin-4(1H)-one can be synthesized by a variety of synthetic methods.
-One of the commonly used methods is to treat 3-nitro2-aminophenol with ketone, and then carry out acid-base neutralization to obtain the target compound.
Safety Information:
- 6-nitroquinazolin-4(1H)-one is an organic compound with certain potential hazards.
-It may irritate the eyes, skin and respiratory system, so avoid contact when handling.
-In operation, it is recommended to take appropriate laboratory safety measures, such as wearing protective gloves, goggles and protective clothing.
-During storage, it should be kept in a dry, cool place, away from fire and combustibles.
Nature:
-6-Nitroquinazolin-4 (1H)-one is a yellow to orange solid.
-It has a high melting point and thermal stability.
-Almost insoluble in water at room temperature, but soluble in some organic solvents such as chloroform, dichloromethane and dimethyl sulfoxide.
Use:
-6-Nitroquinazolin-4 (1H)-one is widely used in the field of organic synthesis.
-It can be used as a pharmaceutical intermediate for the synthesis of various biologically active compounds.
-In addition, it can also be used for the preparation of dyes, pigments and photosensitive materials.
Preparation Method:
- 6-nitroquinazolin-4(1H)-one can be synthesized by a variety of synthetic methods.
-One of the commonly used methods is to treat 3-nitro2-aminophenol with ketone, and then carry out acid-base neutralization to obtain the target compound.
Safety Information:
- 6-nitroquinazolin-4(1H)-one is an organic compound with certain potential hazards.
-It may irritate the eyes, skin and respiratory system, so avoid contact when handling.
-In operation, it is recommended to take appropriate laboratory safety measures, such as wearing protective gloves, goggles and protective clothing.
-During storage, it should be kept in a dry, cool place, away from fire and combustibles.
Last Update：2024-04-09 20:52:54
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Spot supply
Product Name: 6-Nitro-4-quinazolone Visit Supplier Webpage Request for quotationCAS: 6943-17-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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