Name | Alisol B acetate |
Synonyms | Acetylalisol B Alisol B acetate Alisol B 23-acetate, ALISOL B ACETATE(SH) (8α,9β,14β,23S,24R)-23-Acetoxy-24,25-epoxy-11β-hydroxydammar-13(17)-en-3-one (8α,9β,14β,23S,24R)-11β-Hydroxy-23-acetoxy-24,25-epoxy-5α-dammara-13(17)-ene-3-one (23S,24R)-24,25-Epoxy-11b,23-dihydroxy-8a,9b,14b-dammar-13(17)-en-3-one 23-acetate (5xi,8alpha,9xi,11beta,14beta,20xi)-11-hydroxy-3-oxo-24,25-epoxydammar-13(17)-en-23-yl acetate [1-(3,3-dimethyloxiran-2-yl)-3-[(8S,10S,11S,14R)-11-hydroxy-4,4,8,10,14-pentamethyl-3-oxo-1,2,5,6,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-17-yl]butyl] acetate |
CAS | 26575-95-1 |
InChI | InChI=1/C32H50O5/c1-18(16-23(36-19(2)33)27-29(5,6)37-27)20-10-14-31(8)21(20)17-22(34)26-30(7)13-12-25(35)28(3,4)24(30)11-15-32(26,31)9/h18,22-24,26-27,34H,10-17H2,1-9H3/t18-,22+,23+,24+,26+,27-,30+,31+,32+/m1/s1 |
Molecular Formula | C32H50O5 |
Molar Mass | 514.74 |
Density | 1.12±0.1 g/cm3(Predicted) |
Melting Point | 162~163℃ |
Boling Point | 590.7±50.0 °C(Predicted) |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White |
pKa | 14.74±0.70(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.542 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, derived from Alisma orientalis. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
HS Code | 29153900 |
introduction | alisol B acetate is also called alisol B- 23-acetate. Alisma orientale root tuber is widely used in the treatment of kidney diseases as a common clinical medicine of traditional Chinese medicine. The description of clinical changes in kidney disease in modern medicine is consistent with the scope of indications of Alisma orientale described in traditional Chinese medicine, "returning to the kidney, bladder meridian", diuretic, dampness and heat release effects. Studies have suggested that the extract mixture of Alisma orientale and its main active ingredient triterpenoids have the function of stimulating the nuclear receptor FXR, including Alisol B- 23-acetate. |
Biological activity | Alisol B 23-acetate (23-Acetylalismol B) is a triterpene compound that can promote damaged liver regeneration by activating farnicol receptors. |
use | 23-acetyl alisol B has the effects of lowering cholesterol, protecting liver, lowering blood pressure and diuresis. |