Alogliptin Related Compound 28

Alogliptin Related Compound 28 - Names and Identifiers

Name	Benzonitrile,2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-
Synonyms	alogliptina impurity 2 Alogliptin Related Compound 28 2-((6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H) 2-((6-Chloro-3,4-dihydro-3-methyl-2,4-dioxopyrimidin-1(2H)-yl)methyl)benzonitrile 2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h)-pyriMidinyl)Methyl]benzonitrile 2-((6-Chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)benzonitrile Benzonitrile,2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]- Benzonitrile,2-[(6-chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)Methyl]-
CAS	865758-96-9
EINECS	695-742-0

Alogliptin Related Compound 28 - Physico-chemical Properties

Molecular Formula	C13H10ClN3O2
Molar Mass	275.69
Density	1.44
Melting Point	162-164°C
Boling Point	418.0±55.0 °C(Predicted)
Solubility	DMSO (Soluble, Sonicated), Methanol (Slightly, Heated, Sonicated)
Appearance	Solid
Color	White to Off-White
pKa	-3.65±0.40(Predicted)
Storage Condition	2-8°C

Alogliptin Related Compound 28 - Introduction

Benzonitrile,2-[(6-choro-3, 4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-, abbreviated as BCMP, is an organic compound.

Nature:
-Appearance: BCMP is a colorless crystalline solid.
-Solubility: BCMP is soluble in organic solvents such as dimethyl sulfoxide, ethanol and acetonitrile.
-Melting point: The melting point of BCMP is about 122-124°C.

Use:
BCMP has many applications in the chemical field:
-It can be used as an intermediate for the synthesis of amine compounds;
-It can be used to synthesize biologically active compounds, such as anti-cancer drugs;
-It can also be used as a synthetic intermediate for fluorescent probes, luminescent agents and polymer compounds.

Preparation Method:
The preparation method of BCMP can be carried out through the following steps:
1. reaction of toluene with excess trichlorocyanomethane to obtain benzyl trichloromethyl methane.
2. BCMP was obtained by hydrolysis and neutralization of benzyl trichloromethyl methane and urea under alkaline conditions.

Safety Information:
The relevant security information for the BCMP is as follows:
- BCMP in contact with the skin or inhalation may cause allergic reactions, should pay attention to protective measures.
-Avoid contact with strong oxidants to avoid fire or explosion.
-should be kept away from fire, stored in a cool, dry place.
-Wear protective glasses, gloves and masks when using.
-If exposed, flush with plenty of water and seek medical attention immediately.

Last Update：2024-04-09 02:00:48