Apremilast Impurity 33
3-Ethoxy-4-methoxybenzoic acid
CAS: 2651-55-0
Molecular Formula: C10H12O4
Apremilast Impurity 33 - Names and Identifiers
| Name | 3-Ethoxy-4-methoxybenzoic acid |
| Synonyms | AKOS 212-50 RARECHEM AL BE 0687 Apremilast Impurity 33 Apremilast Impurity 24 3-ethoxy-4-methoxybenzoate 3-Ethoxy-4-methoxybenzoic acid 3-ETHOXY-4-METHOXYBENZOIC ACID |
| CAS | 2651-55-0 |
| InChI | InChI=1/C10H12O4/c1-3-14-9-6-7(10(11)12)4-5-8(9)13-2/h4-6H,3H2,1-2H3,(H,11,12)/p-1 |
Apremilast Impurity 33 - Physico-chemical Properties
| Molecular Formula | C10H12O4 |
| Molar Mass | 196.2 |
| Density | 1.178±0.06 g/cm3(Predicted) |
| Melting Point | 156-160°C |
| Boling Point | 316.4±22.0 °C(Predicted) |
| Flash Point | 123°C |
| Vapor Presure | 0.000173mmHg at 25°C |
| pKa | 4.37±0.10(Predicted) |
Apremilast Impurity 33 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
Apremilast Impurity 33 - Introduction
acid is an organic compound with the chemical formula C10H12O4. The following is a description of the properties, uses, preparation methods and safety information of the compound:
Nature:
-Appearance: acid is a colorless to white crystal or crystalline powder.
-Solubility: It is soluble in alcohol, ether and Ester solvents at room temperature, and almost insoluble in water.
Use:
-or acid can be used as an intermediate in organic synthesis, and has applications in the fields of pharmaceuticals, dyes and cosmetics.
-It can also be used as a chelating reagent for metal ion analysis in analytical chemistry.
Method:
The synthesis method of acid usually involves the following steps:
1. First, 3-ethoxy-4-methoxybenzene methyl ether was synthesized as a nitro derivative by Nitro reaction.
2. Next, the nitro derivative is reduced to an amino derivative and then converted to a halogenated derivative.
3. Finally, the halogenated derivative is reacted with sodium carbonate to obtain acid.
Safety Information:
It is generally safe under normal operating conditions. However, appropriate laboratory safety procedures, such as wearing protective glasses, gloves and laboratory coats, should still be used when handling the compound. In addition, avoid inhalation and skin contact, and store properly to prevent fire and explosion. During use, the relevant safe operation guidelines and chemical storage requirements should be followed. In case of accidental contact or inhalation, seek medical attention immediately.
Nature:
-Appearance: acid is a colorless to white crystal or crystalline powder.
-Solubility: It is soluble in alcohol, ether and Ester solvents at room temperature, and almost insoluble in water.
Use:
-or acid can be used as an intermediate in organic synthesis, and has applications in the fields of pharmaceuticals, dyes and cosmetics.
-It can also be used as a chelating reagent for metal ion analysis in analytical chemistry.
Method:
The synthesis method of acid usually involves the following steps:
1. First, 3-ethoxy-4-methoxybenzene methyl ether was synthesized as a nitro derivative by Nitro reaction.
2. Next, the nitro derivative is reduced to an amino derivative and then converted to a halogenated derivative.
3. Finally, the halogenated derivative is reacted with sodium carbonate to obtain acid.
Safety Information:
It is generally safe under normal operating conditions. However, appropriate laboratory safety procedures, such as wearing protective glasses, gloves and laboratory coats, should still be used when handling the compound. In addition, avoid inhalation and skin contact, and store properly to prevent fire and explosion. During use, the relevant safe operation guidelines and chemical storage requirements should be followed. In case of accidental contact or inhalation, seek medical attention immediately.
Last Update：2024-04-09 21:01:54
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Product Name: Apremilast Impurity 33 Visit Supplier Webpage Request for quotationCAS: 2651-55-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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