Astrapterocarpan glucoside
Methylnissolin-3-O-glucoside
CAS: 94367-42-7
Molecular Formula: C23H26O10
Astrapterocarpan glucoside - Names and Identifiers
Astrapterocarpan glucoside - Physico-chemical Properties
| Molecular Formula | C23H26O10 |
| Molar Mass | 462.45 |
| Density | 1.456±0.06 g/cm3(Predicted) |
| Boling Point | 646.3±55.0 °C(Predicted) |
| Appearance | White powder |
| pKa | 12.77±0.70(Predicted) |
| Storage Condition | 2-8℃ |
Astrapterocarpan glucoside - Reference
| Reference Show more | 1. Liu Pengpeng Zhang Fan History Series et al. Determination of eight glycosides and four aglycones in radix astragali processed at different temperatures by UPLC-MS/MS [J]. China pharmacy 2020(3):287-293. 2. Liu Pengpeng, single country, Zhang Fan History series, Jia Tianzhu. UPLC-MS comparison of contents of 12 active components in astragalus membranaceus prepared by directional processing with organic acid [J]. Chinese Journal of Traditional Chinese Medicine, 2020, 45(01):113-118. 3. Liu, Pengpeng, Guoxian, Zhang Fan et al. UPLC-MS comparison of contents of 12 active components in astragalus membranaceus prepared by directional processing with organic acid [J]. Chinese Journal of Traditional Chinese Medicine, 2020 v.45(01):121-126. 4. Sun xiului, Wei Guijie, Wang Hongya, Zhao Wenwen, Zhang Chu, Zhang Ting, Wei Feng, Zhang Yujie. Quality Grade Evaluation of radix astragali based on appearance and internal components [J]. Chinese Journal of Traditional Chinese Medicine, 2021,46(04):966-971. 5. Lagerstroemia Feng. Study on quality grade standard of Zizhou radix astragali decoction pieces [D]. Beijing University of Chinese Medicine, 2020. |
Astrapterocarpan glucoside - Reference Information
| Plant Source: | radix astragali |
| Overview | (6aR,11aR)-9,10-dimethoxy pterostilbene-3-o-β-d-glucoside is one of the extracts of Astragalus mongholicus, which can only be used for scientific research and cannot be used for others as a reference substance for experiments. This paper mainly introduces (6aR,11aR)-9, 10-dimethoxy-pterosanol-3-o-β-d-glucoside basic information, source, structure identification, extraction and separation, use and so on. |
| Basic information | Molecular Weight: 462.45 purity: HPLC ≥ 98% Molecular Structure: |
| Source | Mongolia Astragalus membranaceus Astra bge. var. mongholicus (Bge.) hisao is a plant of the genus Astragalus. Astragalus mongholicus is a variety of Astragalus membranaceus, which is mainly distributed in Inner Mongolia, Shanxi and Northeast provinces in China. The main chemical constituents of Astragalus mongholicus are flavonoids, saponins and polysaccharides. fig.1 astragalus mongholicus |
| Use | as a reference substance for experiments, etc., can only be used for scientific research testing, cannot be used for other FIG. 2 (6aR,11aR)-9,10-dimethoxy Pterostilbene-3-o-β-d-glucoside reference substance used for content determination/identification/pharmacological experiments |
| extraction and separation | astragalus mongholicus decoction pieces 5.0, 10 times the amount of 70% ethanol soak 12 h, reflux extraction 3 times, every Times 2 h, the solvent was recovered under reduced pressure to obtain the extract. The extract was dissolved in appropriate amount of water, followed by extraction with petroleum ether, acetic acid ethyl ester and n-butanol. Ethyl acetate extract (40.3g) was separated by silica gel column chromatography, and separated into 8 components by dichloromethane-methanol (100: 0 → 1: 1) gradient elution,(6a R, 11a R)-9, 10- dimethoxypterosane-3-o-β-d-glucoside by silica gel column chromatography, Sephadex LH-20, ODS compound (30.0 mg)(6aR,11aR)- 9, 10-dimethoxy Pterostilbene-3-o-β-d-glucoside. |
| Structure Identification | (6aR,11aR)-9, 10-dimethoxy-pterosane-3-o-β-d-glucoside: white powder. HR-MS gives m/z 463.161 9 [M + H]. 1H-NMR (300 MHz, DMSO-d6) δ: 7.42 (1H, d, J = 8.4 Hz, H-1), 7.00 (1H, d, J = 8.1 Hz, H-7), 6.72 (1H, dd, J = 8.4, 2.4 Hz, H-2), 5.62 (1H, d, J = 6.9 Hz, H-11a), 6.56 (1H, d, J = 2.4 Hz, H-4), 6.54 (1H, d, J = 8.1 Hz, H-8), 5.30 (1H, d, J = 4.8 Hz, -OH), 5.08 (1H, d J = 4.5 Hz, -OH), 5.01 (1H, d, J = 5.1 Hz, -OH), 4.85 (1H, d, J = 7.5 Hz, H-1′), 4.55 (1H, t, J = 6.0 Hz, -OH), 4.27 (1H, m, H-6), 3.74 (3H, s -OCH3), 3.70 (3H, s, -OCH3), 3.68 (2H, m, H-6, 6a), 3.10~4.11 (6H, m, sugar-H);13C-NMR (75 MHz, DMSO-d6) δ: 158.5 (C-3), 156.2 (C-4a), 152.7 (C- 9), 151.0 (C-11), 133.4 (C-10), 132.0 (C-1), 121.6 (C-6b), 118.8 (C-7), 114.1 (C-11b), 110.5 (C-2), 105.1 (C-8), 104.0 (C-4), 100.3 (C-1′), 78.2 (C-11a), 77.1 (C-5′), 76.5 (C-3′), 73.2 (C-2′), 69.7 (C-4′), 65.8 (C-6), 60.7 (C-6′), 59.9 (10- OCH3) 56.1 (9-OCH3), 39.8 (C-6a). The above data are basically consistent with those reported in the literature [3], so identified compound 8 as (6a R, 11a R)-9, 10-dimethoxy Pterostilbene-3-o-β-d-glucose glycoside. |
| reference | [1] (6aR,11aR)-9, 3-o-β-d-glucoside. Clove Tong. [Citation date: 2017.08.20] [2] Luo Zhou, Su Minzhi, Yan Ming, Shi Guobing, Zhao Qingchun. Studies on the chemical constituents of Astragalus mongholicus [J]. Chinese herbal medicine, 2012,43(03):458-462. [3] Wen Yuhan, Cheng Liang, Zheng Dan, et al. Studies on chemical constituents of Astragalus mongholicus [J]. Practical Medicine and clinic, 2010, 13(2): 115-119. |
Last Update：2024-04-09 21:11:58
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Mobile: 18021002903
QQ: 3008007409
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