Molecular Formula | C26H24FNO5 |
Molar Mass | 449.4708632 |
Density | 1.435±0.06 g/cm3(Predicted) |
Melting Point | >163°C (dec.) |
Boling Point | 661.1±55.0 °C(Predicted) |
Solubility | Chloroform (Slightly), DMSO, Methanol (Very Slightly |
Appearance | Solid |
Color | White to Off-White |
pKa | 10.43±0.70(Predicted) |
Storage Condition | -20°C Freezer, Under inert atmosphere |
In vitro study | Atorvastatin treatment decreases apoptosis of myocardial cells by down-regulating GRP78, caspase-12 and CHOP expression in myocardial cells after myocardial infarction, and the endoplasmic reticulum (ER) stress is activated in response to heart failure and angiotensin II (Ang II) stimulation. |
biological activity | atorblastin epoxytrafuran impure is an Impurity in the oxidative degradation products of Atorvastatin (atorblastin; HY-B0589). Atorblastin is an orally active HMG-CoA reductase inhibitor with the ability to effectively reduce blood lipids. |