Molecular Formula | C15H20O2 |
Molar Mass | 232.32 |
Density | 1.09±0.1 g/cm3(Predicted) |
Melting Point | 150-152 °C(Solv: ethyl ether (60-29-7)) |
Boling Point | 378.0±41.0 °C(Predicted) |
Specific Rotation(α) | (c, 0.2 in CHCl3)+471.6 |
Flash Point | 161.253°C |
Solubility | Soluble in methanol, DMSO and other solvents. |
Vapor Presure | 0mmHg at 25°C |
Appearance | White crystal |
Storage Condition | 2-8℃ |
Refractive Index | 1.535 |
MDL | MFCD09037396 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Atractylodes macrocephala Koidz.. |
Reference Show more | 1. Di Si-rong, Wang Xue, Wang cancan et al. Simultaneous determination of four active components in ganyankang powder by HPLC and its fingerprint [J]. Journal of Shenyang Pharmaceutical University, 2019, 36(04):308-314. 2. Wang Jianjian. Optimization of extraction process of Atractylodes macrocephala lactone Ⅰ,Ⅱ,Ⅲ from Atractylodes macrocephala [J]. Chinese Journal of Experimental prescriptions, 2015. 3. Ouyang Limin, Wang Xinhong, Zhu Simin, etc. Study on the best harvest time of Atractylodes lancea based on AHP-CRITIC method [J]. Chinese traditional medicines, 2020, 042(003):708-713. 4. Ding, Yi, Xue, Xu, Ji-Chang, Wu, Wei, et al. Simultaneous determination of four sesquiterpenes in Atractylodes macrocephala by HPLC [J]. Chinese patent medicine 2020 042(004):927-931. 5. Feng Xin, Zhao Wenjun, Hou Ting, et al. Determination of 14 components in ermiao powder extract by UPLC-MS/MS [J]. Chinese Journal of Experimental prescriptions, 2017, 023(021):79-85. 6. Wenting Chen, Yang Chen, Bo Cui, et al. Feasibility study of gas chromatography "one test and multiple evaluation" for determination of multi-component content in Atractylodes lancea [J]. Chinese Journal of Traditional Chinese Medicine, 2018, 043(003):551-556. 7. Sun jinweng Lili, Xiao Chunping, etc. Quality Analysis of Atractylodes lancea medicinal materials with different growth years by HPLC-one-Test multi-evaluation method combined with color difference principle [J]. China pharmacy 2020 v.31;No.677(11):39-44. 8. Li Qin-yu, Wu Wei-gang, Cui Bo, et al. High performance liquid chromatography combined with multivariate statistical analysis for quality evaluation of Atractylodes lancea [J]. Journal of Pharmaceutical Analysis, 2018, v.38(04):56-66. 9. [IF = 4.556] Song Deng et al."HBD inhibit the Development of coli-Associated Cancer in Mice via IL-6R/STAT3 Signaling Pathway."Int J Mol Sci. 2019 Jan;20(5):1069 10. [IF=4.759] Gao-Yan Tong et al."Analysis of active compounds and geographical origin discrimination of Atractylodes macrocephala Koidz. by using high performance liquid chromatography-diode array detection fingerprints combined with chemometrics."JOURNAL OF CHROMATOGR |
biological activity | Atractylenolide II is a sesquiterpene compound isolated from the dried rhizome of Atractylodes macrocephala, has anti-proliferative activity. |
Use | Atractylodes macrocephala lactone II has the functions of strengthening spleen, replenishing Qi, drying dampness and promoting water, stopping sweat, preventing fetus, anti-inflammatory, anti-tumor, regulates the action of the gastrointestinal tract. for content determination/identification/pharmacological experiments. Pharmacological Efficacy: anti-inflammatory, anti-tumor effect, regulating gastrointestinal function. |