Azithromycin EP Impurity S

Azithromycin EP Impurity S - Names and Identifiers

Name	ErythroMycin A 9,11-IMino Ether
Synonyms	9,11-Imino Ether Azithromycin Impurity 3 Azithromycin EP Impurity S ErythroMycin A 9,11-IMino Ether Azithromycin Impurity R Erythromycin A Azithromycin Impurity R Erythromycin A (9,11-Imino Ether) Erythromycin A 9,11-Imino Ether (Azithromycin ChP Impurity R)
CAS	161193-44-8

Azithromycin EP Impurity S - Physico-chemical Properties

Molecular Formula	C37H66N2O12
Molar Mass	730.94
Density	1.29±0.1 g/cm3(Predicted)
Melting Point	130-131 °C
Boling Point	809.2±65.0 °C(Predicted)
Solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Appearance	Solid
Color	White to Yellow
pKa	12.71±0.70(Predicted)
Storage Condition	Hygroscopic, -20°C Freezer, Under inert atmosphere
Stability	Hygroscopic

Azithromycin EP Impurity S - Introduction

ErythroMycin A 9,11-imino Ether is A derivative of ErythroMycin, which has the following properties:

1. Appearance: ErythroMycin A 9,11-imino Ether is white or slightly yellow crystalline powder.

2. Solubility: It can be dissolved in some organic solvents, such as ethanol and ether.

ErythroMycin A 9,11-imino Ether has A variety of uses in medicine and agriculture:

1. Medical use: ErythroMycin A 9,11-imino Ether has antibacterial activity and can be used to treat some bacterial infections, especially for bacteria that are resistant to other antibiotics.

2. Agricultural use: ErythroMycin A 9,11-imino Ether can be used as an agricultural control of diseases on vegetables, fruits and grain crops. It has the ability to inhibit bacteria and fungi and can be used to control some plant diseases.

The preparation method of ErythroMycin A 9,11-imino Ether is as follows:

1. Obtain erythromycin: first need to obtain Erythromycin as raw material. Erythromycin is a natural antibiotic that can be produced by microbial fermentation.

2. Reaction: Imine ether group is introduced into the chemical structure of erythromycin. Specific synthetic methods use steps such as nucleophilic substitution reactions, reduction reactions, or addition reactions.

The safety information for ErythroMycin A 9,11-imino Ether is as follows:

1. Toxicity: ErythroMycin A 9,11-imino Ether is less toxic to the human body under normal conditions of use, but may cause allergic reactions or other adverse reactions in high doses or in the case of allergies.

2. Environmental impact: ErythroMycin A 9,11-imino Ether has certain environmental toxicity and may have certain effects on aquatic organisms and microorganisms in soil.

3. Safe operation: when using ErythroMycin A 9,11-imino Ether, you should follow the relevant safety operation procedures, and pay attention to prevent and reduce potential risks to the human body and the environment.

Last Update：2024-04-09 01:59:57