B-(2-Fluoro-3-methylphenyl)boronic acid
(2-fluoro-3-methylphenyl)boronic acid
CAS: 762287-58-1
Molecular Formula: C7H8BFO2
B-(2-Fluoro-3-methylphenyl)boronic acid - Names and Identifiers
B-(2-Fluoro-3-methylphenyl)boronic acid - Physico-chemical Properties
| Molecular Formula | C7H8BFO2 |
| Molar Mass | 153.95 |
| Density | 1.20 |
| Melting Point | 160-161℃ |
| Boling Point | 291℃ |
| Flash Point | 130℃ |
| Vapor Presure | 0.000947mmHg at 25°C |
| pKa | 8.42±0.58(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.505 |
B-(2-Fluoro-3-methylphenyl)boronic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| Hazard Note | Irritant |
B-(2-Fluoro-3-methylphenyl)boronic acid - Introduction
(2-fluoro-3-methylphenyl)boronic acid, also known as ((2-fluoro-3-methylphenyl)boronic acid), is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Chemical formula: C7H8BFO2
-Molecular weight: 155.95g/mol
-Appearance: Colorless solid
-Melting Point: 179-183°C
-Boiling point: 332.8°C
-Low solubility in water, soluble in organic solvents such as ethanol, dimethylformamide, etc.
Use:
- (2-fluoro-3-methylphenyl)boronic acid is one of the important raw materials of protease inhibitors and drug intermediates.
-It can be used in organic synthesis reactions, such as phenyl substitution reactions, aldehyde substitution reactions, etc.
Preparation Method:
- (2-fluoro-3-methylphenyl)boronic acid can be obtained by the reaction of benzyl alcohol and hydrofluoric acid, and then prepared by boric acid esterification.
Safety Information:
- (2-fluoro-3-methylphenyl)boronic the toxicity of acid is low, but it is still necessary to pay attention to its safe operation.
-The compound may be irritating to the human body and should be handled with appropriate protective equipment such as gloves and goggles.
-Avoid contact with strong oxidants and store in a dry, well-ventilated place.
Nature:
-Chemical formula: C7H8BFO2
-Molecular weight: 155.95g/mol
-Appearance: Colorless solid
-Melting Point: 179-183°C
-Boiling point: 332.8°C
-Low solubility in water, soluble in organic solvents such as ethanol, dimethylformamide, etc.
Use:
- (2-fluoro-3-methylphenyl)boronic acid is one of the important raw materials of protease inhibitors and drug intermediates.
-It can be used in organic synthesis reactions, such as phenyl substitution reactions, aldehyde substitution reactions, etc.
Preparation Method:
- (2-fluoro-3-methylphenyl)boronic acid can be obtained by the reaction of benzyl alcohol and hydrofluoric acid, and then prepared by boric acid esterification.
Safety Information:
- (2-fluoro-3-methylphenyl)boronic the toxicity of acid is low, but it is still necessary to pay attention to its safe operation.
-The compound may be irritating to the human body and should be handled with appropriate protective equipment such as gloves and goggles.
-Avoid contact with strong oxidants and store in a dry, well-ventilated place.
Last Update：2024-04-09 02:00:48
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CAS: 762287-58-1
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Mobile: 18021002903
QQ: 3008007409
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CAS: 762287-58-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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