BENZYLOXYCARBONYLAMINO-FURAN-2-YL-ACETIC ACID

BENZYLOXYCARBONYLAMINO-FURAN-2-YL-ACETIC ACID - Names and Identifiers

Name	{[(benzyloxy)carbonyl]amino}(furan-2-yl)acetic acid
Synonyms	CBZ-2-AMINO-2-FURACETIC ACID CBZ-2-AMINO-2-FURANACETIC ACID Cbz-2-Amino-2-Furanacetic Acid BENZYLOXYCARBONYLAMINO-FURAN-2-YL-ACETIC ACID {[(benzyloxy)carbonyl]amino}(furan-2-yl)acetic acid 2-(Benzyloxycarbonylamino)-2-(furan-2-yl)acetic acid 2-Furanacetic acid, α-[[(phenylmethoxy)carbonyl]amino]- 2-(2-amino-3-phenylmethoxycarbonyl-3H-furan-2-yl)acetic acid
CAS	61886-78-0
InChI	InChI=1/C14H13NO5/c16-13(9-12-7-4-8-18-12)20-15-14(17)19-10-11-5-2-1-3-6-11/h1-8H,9-10H2,(H,15,17)

BENZYLOXYCARBONYLAMINO-FURAN-2-YL-ACETIC ACID - Physico-chemical Properties

Molecular Formula	C14H13NO5
Molar Mass	275.26
Storage Condition	2-8°C
Refractive Index	1.556

BENZYLOXYCARBONYLAMINO-FURAN-2-YL-ACETIC ACID - Introduction

{[(benzyloxy)carbonyl]amino}(furan-2-yl)acetic acid is an organic compound with the chemical formula C19H17NO5. It is a solid having the form of a white to pale yellow crystal or powder. The following is an introduction to the nature, use, preparation and safety information of {[(benzyloxy)carbonyl]amino}(furan-2-yl)acetic acid:

Nature:
{[(benzyloxy)carbonyl]amino}(furan-2-yl)acetic acid is a compound that protects an amino acid. The amino group of the amino acid is protected as a N-Cbz (dibenzyloxycarbonyl) group, and at the same time, the side chain is connected to the furan group (ie furan ring). It is stable at room temperature, soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane, and insoluble in water.

Use:
{[(benzyloxy)carbonyl]amino}(furan-2-yl)acetic acid is commonly used in peptide synthesis reactions and chemical reactions to protect carboxyl and amino groups in organic synthesis. By introducing a N-Cbz protecting group and a furan group, the amino acid can be effectively protected from side reactions during the reaction. In addition, it can also be used as an intermediate for the generation of specific amide compounds in pharmaceutical and biochemical research.

Preparation Method:
The synthesis of {[(benzyloxy)carbonyl]amino}(furan-2-yl)acetic acid is usually carried out by organic synthesis methods. One of the common preparation methods is to react N-Cbz glycine with furan acid chloride to produce {[(benzyloxy)carbonyl]amino}(furan-2-yl)acetic acid. The preparation process needs to be carried out under an inert atmosphere to avoid side reactions caused by oxygen.

Safety Information:
{[(benzyloxy)carbonyl]amino}(furan-2-yl)acetic acid has low toxicity and danger, but it is still necessary to pay attention to safe operation. Wear appropriate protective equipment to avoid direct contact with skin and eyes when using and handling the compound. In a laboratory environment, standard chemical laboratory practices should be followed to avoid inhalation of aerosols or dust and to maintain good ventilation.

Last Update：2024-04-09 02:00:47