BI 6015 - Names and Identifiers
BI 6015 - Physico-chemical Properties
Molecular Formula | C15H13N3O4S
|
Molar Mass | 331.35 |
Solubility | Soluble in DMSO |
Appearance | Beige powder |
Color | Tan |
Storage Condition | +2C to +8C |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months. |
Use | BI6015 is a small molecule antagonist of Hepatocyte nuclear factor 4α (HNF4α) that has been shown to repress the expression of known HNF4α target genes. |
BI 6015 - Reference
Reference Show more | 1: Mayati A, Le Vee M, Moreau A, Jouan E, Bucher S, Stieger B, Denizot C, Parmentier Y, Fardel O. Protein kinase C-dependent regulation of human hepatic drug transporter expression. Biochem Pharmacol. 2015 Dec 15;98(4):703-17. doi: 10.1016/j.bcp.2015.10.007. PubMed PMID: 26462574. 2: Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, Higginbotham J, Cashman J, Freeze H, Itkin-Ansari P, Dawson MI, Schroeder F, Cang Y, Mercola M, Levine F. HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chem Biol. 2012 Jul 27;19(7):806-18. doi: 10.1016/j.chembiol.2012.05.014. PubMed PMID: 22840769; PubMed Central PMCID: PMC3447631. |
BI 6015 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 3.018 ml | 15.09 ml | 30.18 ml |
5 mM | 0.604 ml | 3.018 ml | 6.036 ml |
10 mM | 0.302 ml | 1.509 ml | 3.018 ml |
5 mM | 0.06 ml | 0.302 ml | 0.604 ml |
Last Update:2024-01-02 23:10:35
BI 6015 - Introduction
2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole is a chemical substance that belongs to the group of organic compounds. The following is a description of the nature, use, preparation and safety information of 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzidazole:
Nature:
-Appearance: 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzimidazole is a solid, which may have different colors, such as white or yellow.
-Solubility: 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzimidazole has good solubility in some organic solvents, but it is almost insoluble in water.
-Stability: 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole is relatively stable at room temperature, but may decompose or oxidize in the presence of high temperature, light or oxygen.
Use:
-Research: 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzimidazole is commonly used in scientific research, especially in some biochemical and pharmaceutical research.
-Coordination compound: 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole can also be used to synthesize metal complexes, these complexes may have important applications in catalytic reactions.
Preparation Method:
-Main synthesis method: 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole has many synthesis methods, one of which is through organic synthesis reaction, such as amidation reaction, acylation reaction, etc.
-Laboratory preparation: Generally, 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole can be synthesized from the corresponding starting material through a series of synthetic steps.
Safety Information:
-Toxicity: There is limited information on the toxicity of 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole, but based on the experience of general chemicals, we need to handle and use it carefully.
-Avoid Contact: When handling 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzimidazole, appropriate laboratory safety measures should be taken, such as wearing gloves and protective glasses with eyepieces, to reduce skin and eye contact.
-Storage: 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzimidazole should be stored in a dry, cool place, away from fire and oxidizing agents.
Please note that for more specific information on the nature, use, formulation and safety of 2-methyl-1-(2-methyll-5-nitrophenyl) sulphonylbenzimidazole, further review of the literature or consultation with chemical experts is required.
Last Update:2024-04-09 15:16:34