BOC-(R)-3-AMINO-4-(2-FURYL)BUTANOIC ACID

BOC-(R)-3-AMINO-4-(2-FURYL)BUTANOIC ACID - Names and Identifiers

Name	Boc-(R)-3-Amino-4-(2-furyl)-butyric acid
Synonyms	RARECHEM AK PT B008 Boc-D-b-HoAla(2-furyl)-OH BOC-D-ALA(2-FURYL)-(C*CH2)OH BOC-D-BETA-HOALA(2-FURYL)-OH BOC-(2-FURYL)-D-BETA-HOMOALANINE BOC-(R)-3-AMINO-4-(2-FURYL)BUTANOIC ACID Boc-(R)-3-Amino-4-(2-furyl)-butyric acid BOC-(R)-3-AMINO-4-(2-FURYL)-BUTYRIC ACID (betaR)-beta-[[(tert-Butoxy)carbonyl]amino]-2-furanbutanoic acid
CAS	270596-33-3

BOC-(R)-3-AMINO-4-(2-FURYL)BUTANOIC ACID - Physico-chemical Properties

Molecular Formula	C13H19NO5
Molar Mass	269.29
Density	1.181
Boling Point	425.0±40.0 °C(Predicted)
pKa	4.39±0.10(Predicted)
Storage Condition	Room Temprature

BOC-(R)-3-AMINO-4-(2-FURYL)BUTANOIC ACID - Risk and Safety

Hazard Class

IRRITANT

BOC-(R)-3-AMINO-4-(2-FURYL)BUTANOIC ACID - Introduction

Boc-(R)-3-Amino-4-(2-furyl)-butyric acid is an organic compound with the chemical structure Boc-(R)-NH-CH(CH₂ CHCOOH)-(2-furyl). The following describes the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline solid
-Molecular weight: 297.34g/mol
-melting point: 140-145 ℃
-Solubility: Soluble in common organic solvents such as dimethyl sulfoxide, dichloromethane and ethanol.

Use:
Boc-(R)-3-Amino-4-(2-furyl)-butyric acid is mainly used in the field of organic synthesis as an important intermediate.
It can be used in the synthesis of drugs, bioactive molecules and peptide compounds.

Preparation Method:
The preparation of Boc-(R)-3-Amino-4-(2-furyl)-butyric acid is generally divided into the following steps:
1. Synthesis of furan ring: chlorobutyric acid and ethanol are heated to react under acid catalysis to generate ethyl 2-fluorobutyrate.
2. Synthesis of Boc-protected amino acids: Ethyl 2-fluorobutyrate and Boc-amino acid were reacted in dimethylformamide to generate ethyl Boc-aminobutyrate.
3. synthesis of target product: Boc-aminobutyric acid ethyl ester and bromoacetic acid were reacted under the catalysis of base to generate Boc-(R)-3-Amino-4-(2-furyl)-butyric acid.

Safety Information:
Boc-(R)-3-Amino-4-(2-furyl)-butyric acid has no apparent risk under routine experimental conditions. However, for the use of any chemical, appropriate laboratory safety measures should still be taken, such as wearing protective glasses and gloves, and avoiding inhalation of gases or contact with skin. If necessary, the MSDS (Safety Data Sheet) of the chemical should be consulted in advance for more detailed safety information.

Last Update：2024-04-09 02:00:49