BOC-1-AMINO-1-CYCLOPROPANE CARBOXYLIC ACID
BOC-1-Amino-1-cyclopropanecarboxylic acid
CAS: 88950-64-5
Molecular Formula: C9H15NO4
BOC-1-AMINO-1-CYCLOPROPANE CARBOXYLIC ACID - Names and Identifiers
BOC-1-AMINO-1-CYCLOPROPANE CARBOXYLIC ACID - Physico-chemical Properties
| Molecular Formula | C9H15NO4 |
| Molar Mass | 201.22 |
| Density | 1.21±0.1 g/cm3(Predicted) |
| Melting Point | 178 °C |
| Boling Point | 347.6±21.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| BRN | 4430628 |
| pKa | 4.04±0.20(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| MDL | MFCD00083257 |
BOC-1-AMINO-1-CYCLOPROPANE CARBOXYLIC ACID - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust. |
| WGK Germany | 3 |
| HS Code | 29242990 |
| Hazard Class | IRRITANT |
BOC-1-AMINO-1-CYCLOPROPANE CARBOXYLIC ACID - Introduction
BOC-1-Amino-1-cyclopropanecarboxylic acid is an organic compound whose chemical formula is C9H15NO4. It is a white solid with a pungent smell. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-The melting point of BOC-1-Amino-1-cyclopropanecarboxylic acid is about 115-118 degrees Celsius.
-It has low solubility in water and is soluble in common organic solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO) and ethanol.
Use:
- BOC-1-Amino-1-cyclopropanecarboxylic acid is an important intermediate in organic synthesis and is often used in the synthesis of drugs and other organic compounds.
-It can be used to synthesize drugs and natural products containing cyclopropane skeleton, such as anti-cancer drugs, antidepressants, etc.
Preparation Method:
-The preparation of BOC-1-Amino-1-cyclopropanecarboxylic acid is generally carried out by the following steps:
1. cyclopropanecarboxylic acid was dissolved in absolute ethanol and reacted with a certain amount of dimethylformamide (DMF) to obtain cyclopropanecarboxylate.
2. The cyclopropane formate reacts with the organic base (such as trimethylamine) in chloroform to generate the BOC-1-Amino-1-cyclopropanecarboxylic acid ester.
3. Finally, the BOC-1-Amino-1-cyclopropanecarboxylic acid ester is converted into BOC-1-Amino-1-cyclopropanecarboxylic acid by hydrolysis reaction.
Safety Information:
- BOC-1-Amino-1-cyclopropanecarboxylic acid is relatively safe under normal operation, but it still needs to follow laboratory safety operation procedures.
-Wear appropriate protective gloves, glasses and protective clothing during access and handling.
-Avoid inhaling gases and fumes from its powder or solution.
-Do not bring the compound into contact with skin or eyes. If contact occurs, rinse immediately with plenty of water and seek medical help.
-Keep the compound away from ignition and combustibles.
Nature:
-The melting point of BOC-1-Amino-1-cyclopropanecarboxylic acid is about 115-118 degrees Celsius.
-It has low solubility in water and is soluble in common organic solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO) and ethanol.
Use:
- BOC-1-Amino-1-cyclopropanecarboxylic acid is an important intermediate in organic synthesis and is often used in the synthesis of drugs and other organic compounds.
-It can be used to synthesize drugs and natural products containing cyclopropane skeleton, such as anti-cancer drugs, antidepressants, etc.
Preparation Method:
-The preparation of BOC-1-Amino-1-cyclopropanecarboxylic acid is generally carried out by the following steps:
1. cyclopropanecarboxylic acid was dissolved in absolute ethanol and reacted with a certain amount of dimethylformamide (DMF) to obtain cyclopropanecarboxylate.
2. The cyclopropane formate reacts with the organic base (such as trimethylamine) in chloroform to generate the BOC-1-Amino-1-cyclopropanecarboxylic acid ester.
3. Finally, the BOC-1-Amino-1-cyclopropanecarboxylic acid ester is converted into BOC-1-Amino-1-cyclopropanecarboxylic acid by hydrolysis reaction.
Safety Information:
- BOC-1-Amino-1-cyclopropanecarboxylic acid is relatively safe under normal operation, but it still needs to follow laboratory safety operation procedures.
-Wear appropriate protective gloves, glasses and protective clothing during access and handling.
-Avoid inhaling gases and fumes from its powder or solution.
-Do not bring the compound into contact with skin or eyes. If contact occurs, rinse immediately with plenty of water and seek medical help.
-Keep the compound away from ignition and combustibles.
Last Update：2024-04-09 21:00:56
Supplier List
Spot supply
Product Name: 1-[(Tert-Butoxycarbonyl)Amino]Cyclopropanecarboxylic Acid Visit Supplier Webpage Request for quotationCAS: 88950-64-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: 1-[(Tert-Butoxycarbonyl)Amino]Cyclopropanecarboxylic Acid Visit Supplier Webpage Request for quotationCAS: 88950-64-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History