BOC-2-CARBOXYPIPERAZINE

BOC-2-CARBOXYPIPERAZINE - Names and Identifiers

Name	(S)-(-)-2-Piperazinecarboxylic acid
Synonyms	BOC-2-CARBOXYPIPERAZINE (S)-Piperazine-2-carboxylic acid 2-(S)-Piperazine carboxylic acid (2S)-piperazine-2-carboxylic acid 1-BOC-PIPERAZINE-2-CARBOXYLIC ACID (S)-(-)-2-Piperazinecarboxylic acid (S)-PIPERAZINE-2-CARBOXYLIC ACID 2HCL 2-PIPERAZINECARBOXYLIC ACID, (S)-, DIHYDROCHLORIDE (S)-(-)-2-PIPERAZINECARBOXYLIC ACID DIHYDROCHLORIDE PIPERAZINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-PIPERAZINECARBOXYLIC ACID, DIHYDROCHLORIDE, (2S)-
CAS	147650-70-2
InChI	InChI=1/C5H10N2O2/c8-5(9)4-3-6-1-2-7-4/h4,6-7H,1-3H2,(H,8,9)/t4-/m0/s1

BOC-2-CARBOXYPIPERAZINE - Physico-chemical Properties

Molecular Formula	C5H10N2O2
Molar Mass	130.15
Density	1.174±0.06 g/cm3(Predicted)
Melting Point	243-247°C (dec.)
Boling Point	313.6±37.0 °C(Predicted)
Flash Point	143.5°C
Vapor Presure	0.000107mmHg at 25°C
pKa	1.90±0.20(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.476

BOC-2-CARBOXYPIPERAZINE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
FLUKA BRAND F CODES	3-10

BOC-2-CARBOXYPIPERAZINE - Introduction

(S)-(-)-2-Piperazinecarboxylic acid is an organic compound with the chemical formula C6H7NO2. The following is an introduction to its nature, use, preparation and safety information:

Nature:
(S)-(-)-2-Piperazinecarboxylic acid is a colorless crystalline solid with a melting point of about 215-220°C. It has two chiral centers and therefore exists as a stereoisomer (R)-piperazine-2-carboxylic acid. It can be dissolved in water and some organic solvents, such as alcohols and ketones.

Use:
(S)-(-)-2-Piperazinecarboxylic acid has certain applications in the field of medicine. It is an intermediate of imipramine anesthetics and can be used to synthesize a variety of drugs, including imipramine, ketotifen and promethazine. In addition, it can also be used as a catalyst in the synthesis of pesticides and other organic synthesis reactions.

Method:
There are many ways to prepare (S)-(-)-2-Piperazinecarboxylic acid, one of which is commonly used by (S)-Acetyl ketone is obtained by oxidation and appropriate carboxylation reaction. The specific synthetic route also involves the specific conditions of chemical synthesis and the choice of catalyst.

Safety Information:
(S)-(-)-2-Piperazinecarboxylic acid has low toxicity and generally does not have obvious harm. However, as a chemical substance, it still needs to be used and handled correctly. During operation, wear appropriate protective measures, such as gloves, glasses and protective clothing, and avoid inhalation of aerosols and skin contact. If ingested by mistake or exposure occurs, seek medical attention immediately and provide detailed information to the physician with the compound's safety data sheet.

Last Update：2024-04-09 20:52:54