Molecular Formula | C18H13F6NO4S |
Molar Mass | 453.36 |
Density | 1.49±0.1 g/cm3(Predicted) |
Boling Point | 490.6±45.0 °C(Predicted) |
Solubility | DMSO : ≥ 34 mg/mL (75.00 mM) |
Storage Condition | Store at +4°C |
Use | BAY-59-3074 is a novel cannabinoid CB1/CB2 receptor partial agonist with analgesic properties. It displays anti-hyperalgesic and antiallodynic properties in rat models of chronic neuropathic and inflammatory pain. |
Reference Show more | 1: Teng H, Thakur GA, Makriyannis A. Conformationally constrained analogs of BAY 59-3074 as novel cannabinoid receptor ligands. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5999-6002. doi: 10.1016/j.bmcl.2011.07.017. Epub 2011 Jul 23. PubMed PMID: 21880487; PubMed Central PMCID: PMC3693451. 2: De Vry J, Jentzsch KR. Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in the rat. Eur J Pharmacol. 2004 Nov 28;505(1-3):127-33. PubMed PMID: 15556145. 3: De Vry J, Denzer D, Reissmueller E, Eijckenboom M, Heil M, Meier H, Mauler F. 3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl-4,4,4-trifluoro-1-butanesulfonate (BAY 59-3074): a novel cannabinoid Cb1/Cb2 receptor partial agonist with antihyperalgesic and antiallodynic effects. J Pharmacol Exp Ther. 2004 Aug;310(2):620-32. Epub 2004 May 12. PubMed PMID: 15140913. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.206 ml | 11.029 ml | 22.058 ml |
5 mM | 0.441 ml | 2.206 ml | 4.412 ml |
10 mM | 0.221 ml | 1.103 ml | 2.206 ml |
5 mM | 0.044 ml | 0.221 ml | 0.441 ml |