Benzamide, 4-cyano-N-cyclopropyl-N-(2-thienylmethyl)-
4-cyano-N-cyclopropyl-N-[(thiophen-2-yl)methyl]benzamide
CAS: 1210906-48-1
Molecular Formula: C16H14N2OS
Benzamide, 4-cyano-N-cyclopropyl-N-(2-thienylmethyl)- - Names and Identifiers
Benzamide, 4-cyano-N-cyclopropyl-N-(2-thienylmethyl)- - Physico-chemical Properties
| Molecular Formula | C16H14N2OS |
| Molar Mass | 282.36 |
| Solubility | Soluble in DMSO |
| Storage Condition | -20℃ |
| Use | ZINC30303842 is a NSD2-PWWP1 antagonist,which binds to the NSD2-PWWP1 domain with a Kd of 3.4 μM and abrogates histone H3K36me2 binding to the PWWP1 domain in cells. |
| In vitro study | MR837 is a NSD2-PWWP1 inhibitor. |
Benzamide, 4-cyano-N-cyclopropyl-N-(2-thienylmethyl)- - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.542 ml | 17.708 ml | 35.416 ml |
| 5 mM | 0.708 ml | 3.542 ml | 7.083 ml |
| 10 mM | 0.354 ml | 1.771 ml | 3.542 ml |
| 5 mM | 0.071 ml | 0.354 ml | 0.708 ml |
Last Update：2024-01-02 23:10:35
Benzamide, 4-cyano-N-cyclopropyl-N-(2-thienylmethyl)- - Reference Information
| biological activity | MR837 is a NSD2-PWWP1 inhibitor. MR837 can bind to the human nuclear receptor binding SET domain protein (PWWP domain). |
| in vitro study | MR837 is a NSD2-PWWP1 inhibitor. |
Last Update：2024-04-09 18:58:34
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CAS: 1210906-48-1
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Mobile: 18021002903
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CAS: 1210906-48-1
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Mobile: 18021002903
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