Benzamide, N,N-diethyl-2-hydroxy-
N,N-diethylsalicylamide
CAS: 19311-91-2
Molecular Formula: C11H15NO2
Benzamide, N,N-diethyl-2-hydroxy- - Names and Identifiers
| Name | N,N-diethylsalicylamide |
| Synonyms | Ai3-33468 AI3-33468 Brn 2835473 BRN 2835473 Salicyldiethylamide n,n-diethyl-salicylamid N,N-diethylsalicylamide N,N-DIETHYLSALICYLAMIDE Salicylamide, N,N-diethyl- 4-methyl-3,5-dinitroaniline o-hydroxy-n,n-diethylbenzamide o-Hydroxy-N,N-diethylbenzamide n,n-diethyl-2-hydroxy-benzamid 2-Hydroxy-N,N-diethylbenzamide Benzamide, N,N-diethyl-2-hydroxy- 4-10-00-00170 (Beilstein Handbook Reference) |
| CAS | 19311-91-2 |
| EINECS | 242-955-8 |
| InChI | InChI=1/C7H7N3O4/c1-4-6(9(11)12)2-5(8)3-7(4)10(13)14/h2-3H,8H2,1H3 |
Benzamide, N,N-diethyl-2-hydroxy- - Physico-chemical Properties
| Molecular Formula | C11H15NO2 |
| Molar Mass | 193.24 |
| Density | 1.096 |
| Melting Point | 93-97 °C (lit.) |
| Boling Point | 340℃ |
| Flash Point | 159℃ |
| Vapor Presure | 4.67E-06mmHg at 25°C |
| Appearance | Crystalline Powder |
| Color | White to tan |
| pKa | 8.73±0.30(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.5080 (estimate) |
Benzamide, N,N-diethyl-2-hydroxy- - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | VN7320000 |
Benzamide, N,N-diethyl-2-hydroxy- - Introduction
N,N-diethylsalicylamide(N,N-diethylsalicylamide) is a compound whose chemical formula is C12H17NO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
N,N-diethylsalicylamide is a colorless to light yellow crystal or crystalline powder. It is soluble in organic solvents such as ethanol, ether and chloroform at room temperature, and slightly soluble in water. The compound has an aromatic taste similar to that of salicylic acid.
Use:
N,N-diethylsalicylamide has certain applications in the field of medicine. It can be used as a topical painkiller and anti-inflammatory to relieve symptoms such as muscle aches and arthritis. In addition, it is also an adjunct drug in the treatment of chronic pain.
Method:
N,N-diethylsalicylamide can be prepared by the reaction of Salicylamide and diethylamine. The specific preparation method is to dissolve an appropriate amount of Salicylamide and diethylamine in ethanol, react for a period of time, and then obtain the target product by crystallization or vacuum distillation.
Safety Information:
N,N-diethylsalicylamide generally have better safety under normal use conditions. However, as a chemical substance, it is still necessary to pay attention to the following matters:
1. Avoid prolonged or extensive exposure to skin, eyes and mucous membranes to prevent irritation.
2. In use should pay attention to proper ventilation, avoid inhalation of dust or gas.
3. Contact with oxidants and strong acids should be avoided to avoid dangerous reactions.
4. Storage should be kept in a dry, cool and well-ventilated place, away from fire and high temperature.
Nature:
N,N-diethylsalicylamide is a colorless to light yellow crystal or crystalline powder. It is soluble in organic solvents such as ethanol, ether and chloroform at room temperature, and slightly soluble in water. The compound has an aromatic taste similar to that of salicylic acid.
Use:
N,N-diethylsalicylamide has certain applications in the field of medicine. It can be used as a topical painkiller and anti-inflammatory to relieve symptoms such as muscle aches and arthritis. In addition, it is also an adjunct drug in the treatment of chronic pain.
Method:
N,N-diethylsalicylamide can be prepared by the reaction of Salicylamide and diethylamine. The specific preparation method is to dissolve an appropriate amount of Salicylamide and diethylamine in ethanol, react for a period of time, and then obtain the target product by crystallization or vacuum distillation.
Safety Information:
N,N-diethylsalicylamide generally have better safety under normal use conditions. However, as a chemical substance, it is still necessary to pay attention to the following matters:
1. Avoid prolonged or extensive exposure to skin, eyes and mucous membranes to prevent irritation.
2. In use should pay attention to proper ventilation, avoid inhalation of dust or gas.
3. Contact with oxidants and strong acids should be avoided to avoid dangerous reactions.
4. Storage should be kept in a dry, cool and well-ventilated place, away from fire and high temperature.
Last Update：2024-04-09 20:45:29
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CAS: 19311-91-2
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