Benzene, 1-chloro-3-fluoro-2-nitro-
2-Chloro-6-fluoronitrobenzene
CAS: 64182-61-2
Molecular Formula: C6H3ClFNO2
Benzene, 1-chloro-3-fluoro-2-nitro- - Names and Identifiers
| Name | 2-Chloro-6-fluoronitrobenzene |
| Synonyms | 264-723-5 2-Chloro-6-fluoronitrobenzene 2-CHLORO-6-FLUORONITROBENZENE 2-fluoro-6-chloronitrobenzene 6-chloro-2-fluoro-nitrobenzene 1-Chloro-3-fluoro-2-nitrobenzene 1-chloro-3-fluoro-2-nitrobenzene 1-Fluoro-2-nitro-3-chlorobenzene Benzene, 1-chloro-3-fluoro-2-nitro- |
| CAS | 64182-61-2 |
| EINECS | 264-723-5 |
| InChI | InChI=1/C6H3ClFNO2/c7-4-2-1-3-5(8)6(4)9(10)11/h1-3H |
Benzene, 1-chloro-3-fluoro-2-nitro- - Physico-chemical Properties
| Molecular Formula | C6H3ClFNO2 |
| Molar Mass | 175.54 |
| Density | 1.494±0.06 g/cm3(Predicted) |
| Boling Point | 245.1±20.0 °C(Predicted) |
| Flash Point | 102°C |
| Vapor Presure | 0.0459mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.554 |
Benzene, 1-chloro-3-fluoro-2-nitro- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Note | Irritant |
Benzene, 1-chloro-3-fluoro-2-nitro- - Introduction
It is an organic compound with the chemical formula C6H3ClFNO2. It is a solid powder, colorless and odorless. The following is a description of the properties, uses, methods of manufacture and safety information:
Nature:
-Appearance: Colorless to light yellow crystalline powder.
-Melting point: 56-58°C.
-Boiling point: 235-236°C.
-Density: 1.54g/cm³.
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, methanol, etc.
Use:
-It is often used as an intermediate for substitution reactions and amination reactions in organic synthesis reactions.
-It can be used to prepare pesticides, dyes, medicines and other organic compounds.
Preparation Method:
It can be prepared by 2-chloro-6-fluoro substitution reaction of benzene. The specific preparation method can be divided into the following steps:
1. Benzene is reacted with sulfuric acid and concentrated nitric acid to obtain nitrobenzene.
2. reaction of nitrobenzene with cuprous chloride, ferrous chloride or ferric chloride to obtain 2-chloro-6-nitrobenzene.
3. Finally, 2-chloro-6-nitrobenzene is reacted with hydrofluoric acid to obtain fluoric acid.
Safety Information:
-is an organic compound that should follow general laboratory safety practices.
-Avoid direct contact with skin, eyes and respiratory tract during treatment.
-Wear protective equipment such as lab gloves, goggles and masks.
-When storing, please keep it in a sealed container, away from fire and oxidizing agents.
-In case of leakage, it should be cleaned up in time and prevented from entering the water source or sewage outlet.
Nature:
-Appearance: Colorless to light yellow crystalline powder.
-Melting point: 56-58°C.
-Boiling point: 235-236°C.
-Density: 1.54g/cm³.
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, methanol, etc.
Use:
-It is often used as an intermediate for substitution reactions and amination reactions in organic synthesis reactions.
-It can be used to prepare pesticides, dyes, medicines and other organic compounds.
Preparation Method:
It can be prepared by 2-chloro-6-fluoro substitution reaction of benzene. The specific preparation method can be divided into the following steps:
1. Benzene is reacted with sulfuric acid and concentrated nitric acid to obtain nitrobenzene.
2. reaction of nitrobenzene with cuprous chloride, ferrous chloride or ferric chloride to obtain 2-chloro-6-nitrobenzene.
3. Finally, 2-chloro-6-nitrobenzene is reacted with hydrofluoric acid to obtain fluoric acid.
Safety Information:
-is an organic compound that should follow general laboratory safety practices.
-Avoid direct contact with skin, eyes and respiratory tract during treatment.
-Wear protective equipment such as lab gloves, goggles and masks.
-When storing, please keep it in a sealed container, away from fire and oxidizing agents.
-In case of leakage, it should be cleaned up in time and prevented from entering the water source or sewage outlet.
Last Update：2024-04-09 21:00:56
