Benzeneethanol, β,β,2,6-tetrafluoro-
2-(2,6-difluorophenyl)-2,2-difluoroethan-1-ol
CAS: 1581274-20-5
Molecular Formula: C8H6F4O
Benzeneethanol, β,β,2,6-tetrafluoro- - Names and Identifiers
| Name | 2-(2,6-difluorophenyl)-2,2-difluoroethan-1-ol |
| Synonyms | Benzeneethanol, β,β,2,6-tetrafluoro- 2-(2,6-difluorophenyl)-2,2-difluoroethan-1-ol |
| CAS | 1581274-20-5 |
Benzeneethanol, β,β,2,6-tetrafluoro- - Physico-chemical Properties
| Molecular Formula | C8H6F4O |
| Molar Mass | 194.13 |
| Density | 1.387±0.06 g/cm3(Predicted) |
| Boling Point | 252.5±35.0 °C(Predicted) |
| pKa | 13.05±0.10(Predicted) |
Benzeneethanol, β,β,2,6-tetrafluoro- - Introduction
2-(2,6-difluorophenyl)-2,2-difluoroethan-1-ol is an organic compound also known as 2-(2,6-dfp) -2,2-dfe-1-OL. Its molecular formula is C8H6F4O and its molecular weight is 198.13g/mol.
Nature:
-Appearance: colorless liquid
-Boiling point: 82-83 ° C
-Melting point:-10 ° C
-Density: 1.3g/cm³
-Solubility: Soluble in many organic solvents
Use:
2-(2,6-difluorophenyl)-2,2-difluoroethan-1-ol is widely used in the fields of organic synthesis and pharmaceutical research. It is an important intermediate and is often used as a starting material for the synthesis of drugs, pesticides and other organic compounds.
Method:
2-(2,6-difluorophenyl)-2,2-difluoroethan-1-ol has many preparation methods, one of which is obtained by hydrogenation and reduction of 2,6-difluorobenzoic acid. The specific steps are as follows:
1. Dissolve 2,6-difluorobenzoic acid in alcohol (such as ethanol or isopropanol).
2. Add appropriate amount of hydrogen and catalyst (such as platinum, palladium, etc.).
3. Stir the reaction mixture at an appropriate temperature for a period of time.
4. The product was obtained by filtration and purified by distillation.
Safety Information:
2-(2,6-difluorophenyl)-2,2-difluoroethan-1-ol is generally of lower risk when used correctly. However, as laboratory reagents, it is still necessary to take appropriate safety measures, such as wearing protective gloves, glasses and laboratory clothes. In addition, it should be used in a well-ventilated laboratory environment and avoid breathing its vapors. If skin contact or inhalation occurs, rinse immediately with plenty of water and seek medical assistance.
Nature:
-Appearance: colorless liquid
-Boiling point: 82-83 ° C
-Melting point:-10 ° C
-Density: 1.3g/cm³
-Solubility: Soluble in many organic solvents
Use:
2-(2,6-difluorophenyl)-2,2-difluoroethan-1-ol is widely used in the fields of organic synthesis and pharmaceutical research. It is an important intermediate and is often used as a starting material for the synthesis of drugs, pesticides and other organic compounds.
Method:
2-(2,6-difluorophenyl)-2,2-difluoroethan-1-ol has many preparation methods, one of which is obtained by hydrogenation and reduction of 2,6-difluorobenzoic acid. The specific steps are as follows:
1. Dissolve 2,6-difluorobenzoic acid in alcohol (such as ethanol or isopropanol).
2. Add appropriate amount of hydrogen and catalyst (such as platinum, palladium, etc.).
3. Stir the reaction mixture at an appropriate temperature for a period of time.
4. The product was obtained by filtration and purified by distillation.
Safety Information:
2-(2,6-difluorophenyl)-2,2-difluoroethan-1-ol is generally of lower risk when used correctly. However, as laboratory reagents, it is still necessary to take appropriate safety measures, such as wearing protective gloves, glasses and laboratory clothes. In addition, it should be used in a well-ventilated laboratory environment and avoid breathing its vapors. If skin contact or inhalation occurs, rinse immediately with plenty of water and seek medical assistance.
Last Update：2024-04-09 20:52:54
