Benzenesulfonamide, 4-(3-methyl-5-phenyl-4-isoxazolyl)-
4-(3-methyl-4-phenylisoxazol-5-yl)benzenesulfonamide
CAS: 181695-84-1
Molecular Formula: C16H14N2O3S
Benzenesulfonamide, 4-(3-methyl-5-phenyl-4-isoxazolyl)- - Names and Identifiers
Benzenesulfonamide, 4-(3-methyl-5-phenyl-4-isoxazolyl)- - Physico-chemical Properties
| Molecular Formula | C16H14N2O3S |
| Molar Mass | 314.36 |
| Density | 1.303±0.06 g/cm3(Predicted) |
| Boling Point | 479.0±55.0 °C(Predicted) |
| pKa | 9.83±0.10(Predicted) |
| Storage Condition | -20℃ |
Benzenesulfonamide, 4-(3-methyl-5-phenyl-4-isoxazolyl)- - Introduction
4-(benzenesulfonamide) (4-(benzenesulfonamide), also known as parecoxib impurity 39, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-chemical formula: C15H13N2O3S
-Molecular weight: 299.34g/mol
-Appearance: White solid
-Melting point: About 185-188 ° C
-Solubility: Soluble in some organic solvents, such as ethanol and dimethyl sulfoxide
Use:
4-(benzenesulfonamide) exists as an impurity in the basic structure of parecoxib (a non-steroidal anti-inflammatory drug) in the pharmaceutical field. Parecoxib is mainly used to treat arthritis and other inflammation-related diseases.
Method:
4-(benzenesulfonamide) The preparation method of benzenesulfonamide can be obtained by the reaction of aniline and nitrous acid to obtain phenylnitrosamine, and then through cyclization and Amination Reactions, the impurity 39 of parecoxib is generated.
Safety Information:
4-(benzenesulfonamide) has limited safety information, so its use and handling need to be strictly controlled. The substance may be irritating and sensitizing and may cause damage to the skin and eyes. When in use, wear suitable personal protective equipment, including laboratory gloves and protective glasses. At the same time, follow Good Laboratory Practices and ensure that the room is well ventilated. If there is a risk of diffusion or inhalation of impurities 39, take appropriate precautions in a timely manner. Before use, you should read and understand the relevant safety data forms in detail and consult a professional.
Nature:
-chemical formula: C15H13N2O3S
-Molecular weight: 299.34g/mol
-Appearance: White solid
-Melting point: About 185-188 ° C
-Solubility: Soluble in some organic solvents, such as ethanol and dimethyl sulfoxide
Use:
4-(benzenesulfonamide) exists as an impurity in the basic structure of parecoxib (a non-steroidal anti-inflammatory drug) in the pharmaceutical field. Parecoxib is mainly used to treat arthritis and other inflammation-related diseases.
Method:
4-(benzenesulfonamide) The preparation method of benzenesulfonamide can be obtained by the reaction of aniline and nitrous acid to obtain phenylnitrosamine, and then through cyclization and Amination Reactions, the impurity 39 of parecoxib is generated.
Safety Information:
4-(benzenesulfonamide) has limited safety information, so its use and handling need to be strictly controlled. The substance may be irritating and sensitizing and may cause damage to the skin and eyes. When in use, wear suitable personal protective equipment, including laboratory gloves and protective glasses. At the same time, follow Good Laboratory Practices and ensure that the room is well ventilated. If there is a risk of diffusion or inhalation of impurities 39, take appropriate precautions in a timely manner. Before use, you should read and understand the relevant safety data forms in detail and consult a professional.
Last Update：2024-04-09 21:11:58
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Product Name: Parecoxib Impurity 43 Visit Supplier Webpage Request for quotationCAS: 181695-84-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 4-(3-methyl-4-phenylisoxazol-5-yl)benzenesulfonamide Visit Supplier Webpage Request for quotation
CAS: 181695-84-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 181695-84-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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