Benzenesulfonyl chloride, 2-bromo-5-(trifluoromethyl)-

Benzenesulfonyl chloride, 2-bromo-5-(trifluoromethyl)- - Names and Identifiers

Name	2-Bromo-5-(trifluoromethyl)benzenesulphonyl chloride
Synonyms	4-Bromo-3-(chlorosulphonyl)benzotrifluoride 2-BROMO-5-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE 2-bromo-5-(trifluoromethyl)benzenesulfonyl chloride 2-Bromo-5-(trifluoromethyl)benzenesulphonyl chloride 2-BROMO-5-(TRIFLUOROMETHYL)BENZENESULPHONYL CHLORIDE Benzenesulfonyl chloride, 2-bromo-5-(trifluoromethyl)- 2-bromo-5-(trifluoromethyl)benzene-1-sulfonyl chloride 4-Bromo-3-(chlorosulphonyl)benzotrifluoride, 4-Bromo-3-(chlorosulphonyl)-alpha,alpha,alpha-trifluorotoluene
CAS	176225-08-4
InChI	InChI=1/C7H3BrClF3O2S/c8-5-2-1-4(7(10,11)12)3-6(5)15(9,13)14/h1-3H

Benzenesulfonyl chloride, 2-bromo-5-(trifluoromethyl)- - Physico-chemical Properties

Molecular Formula	C7H3BrClF3O2S
Molar Mass	323.51
Density	1.854 g/mL at 25 °C (lit.)
Boling Point	230-231 °C (lit.)
Flash Point	>230°F
Vapor Presure	0.000435mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Sensitive	Moisture Sensitive
Refractive Index	n20/D >1.5290(lit.)
MDL	MFCD03094395

Benzenesulfonyl chloride, 2-bromo-5-(trifluoromethyl)- - Risk and Safety

Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S20 - When using, do not eat or drink.
UN IDs	UN 1760 8/PG 3
WGK Germany	3
HS Code	29049090
Hazard Note	Irritant
Hazard Class	8
Packing Group	II

Benzenesulfonyl chloride, 2-bromo-5-(trifluoromethyl)- - Introduction

2-Bromo-5-(trifluoromethyl)benzenesulphonyl chloride is an organic compound with the chemical formula C7H3BrF3O2SCl. It is a colorless solid with a strong pungent odor. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless solid
-Solubility: Soluble in organic solvents such as ether, chloroform and dichloromethane
-Melting point: About 60-65 ℃
-Boiling point: About 200 ℃

Purpose: 2-Bromo-5-(trifluoromethyl) benzensulphonyl chloride can be used as an important reagent and intermediate in organic synthesis. It has the ability to help introduce a sulfonyl chloride group into a compound and is commonly used in certain steps in organic synthesis reactions.

Preparation method: 2-Bromo-5-(trifluoromethyl)benzenesulphonyl chloride is usually prepared by the following method: firstly, reacting 2-Bromo-5-(trifluoromethyl) benzenesulfonic acid with phosphorus oxychloride, A phosphoryl chloride type intermediate is formed, which is then reacted with thionyl chloride to give the final product.

Safety information: The following should be noted when dealing with 2-Bromo-5-(trifluoromethyl)benzenesulphonyl chloride:
-It is an irritating chemical that may irritate the eyes, skin and respiratory tract. Avoid direct contact with skin, eyes and respiratory tract, and wear personal protective equipment.
-Pay attention to the use of ventilation facilities during operation to ensure that the operating area is well ventilated.
-should be stored in a dry, ventilated place, away from heat and fire.
-When using and handling the substance, all relevant safety procedures and regulations should be observed.

Please note that when using and handling chemicals, you should follow relevant safety procedures and guidelines, and take appropriate personal protective measures. The above information is for reference only, please carry out specific safety assessment and understanding before actual operation.

Last Update：2024-04-10 22:29:15