Benzoic acid, 2-amino-5-methoxy-4-(phenylmethoxy)-, phenylmethyl ester
Benzyl 2-amino-4-(benzyloxy)-5-methoxybenzoate
CAS: 205259-41-2
Molecular Formula: C22H21NO4
Benzoic acid, 2-amino-5-methoxy-4-(phenylmethoxy)-, phenylmethyl ester - Names and Identifiers
| Name | Benzyl 2-amino-4-(benzyloxy)-5-methoxybenzoate |
| Synonyms | LogP CEDI-014 Benzyl 2-amino-4-(benzyloxy)-5-methoxybenzoate 2-amino-5-methoxy-4-phenylmethoxybenzoic acid (phenylmethyl) ester Benzoic acid, 2-amino-5-methoxy-4-(phenylmethoxy)-, phenylmethyl ester |
| CAS | 205259-41-2 |
| InChI | InChI=1/C22H21NO4/c1-25-20-12-18(22(24)27-15-17-10-6-3-7-11-17)19(23)13-21(20)26-14-16-8-4-2-5-9-16/h2-13H,14-15,23H2,1H3 |
Benzoic acid, 2-amino-5-methoxy-4-(phenylmethoxy)-, phenylmethyl ester - Physico-chemical Properties
| Molecular Formula | C22H21NO4 |
| Molar Mass | 363.41 |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| Boling Point | 544.7±45.0 °C(Predicted) |
| Flash Point | 216.221°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 2?+-.0.10(Predicted) |
| Refractive Index | 1.617 |
Benzoic acid, 2-amino-5-methoxy-4-(phenylmethoxy)-, phenylmethyl ester - Introduction
Benzyl 2-amino-4-(benzyloxy)-5-methoxybenzoate is an organic compound with the chemical formula C19H21NO4. It is a white solid, soluble in organic solvents such as alcohol, chloroform and ether. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White solid
-Molecular weight: 331.38g/mol
-Melting point: About 100-102 ° C
-Boiling point: About 400 ° C (decomposition)
-Density: about 1.24g/cm³
-Solubility: Soluble in alcohol, chloroform and ether, slightly soluble in water
Use:
Benzyl 2-amino-4-(benzyloxy)-5-methoxybenzoate can be used as an important intermediate in organic synthesis. It can be used to prepare other organic compounds, such as drugs, dyes and pesticides.
Method:
Benzyl 2-amino-4-(benzyloxy)-5-methoxybenzoate can be synthesized by the following steps:
1.2-amino -4-(benzyloxy)-5-methoxybenzoic acid and excess benzyl alcohol reaction, the esterification product.
2. The esterification product is reacted with an excess of sulfenic acid to produce a chlorinated product.
3. Under alkaline conditions, the chlorinated product reacts with methyl bromide to generate the target product.
Safety Information:
Benzyl 2-amino-4-(benzyloxy)-5-methoxybenzoate has certain safety under normal use conditions, but the following matters still need to be paid attention:
-May be irritating to the eyes, skin and respiratory system, so use should be careful to avoid contact.
-Observe appropriate safety measures during operation, such as wearing appropriate protective equipment (gloves, goggles, etc.).
-Should be stored in a dry, cool place and avoid contact with oxidants and acids.
-When handling this compound, follow local regulations and safe practices.
Nature:
-Appearance: White solid
-Molecular weight: 331.38g/mol
-Melting point: About 100-102 ° C
-Boiling point: About 400 ° C (decomposition)
-Density: about 1.24g/cm³
-Solubility: Soluble in alcohol, chloroform and ether, slightly soluble in water
Use:
Benzyl 2-amino-4-(benzyloxy)-5-methoxybenzoate can be used as an important intermediate in organic synthesis. It can be used to prepare other organic compounds, such as drugs, dyes and pesticides.
Method:
Benzyl 2-amino-4-(benzyloxy)-5-methoxybenzoate can be synthesized by the following steps:
1.2-amino -4-(benzyloxy)-5-methoxybenzoic acid and excess benzyl alcohol reaction, the esterification product.
2. The esterification product is reacted with an excess of sulfenic acid to produce a chlorinated product.
3. Under alkaline conditions, the chlorinated product reacts with methyl bromide to generate the target product.
Safety Information:
Benzyl 2-amino-4-(benzyloxy)-5-methoxybenzoate has certain safety under normal use conditions, but the following matters still need to be paid attention:
-May be irritating to the eyes, skin and respiratory system, so use should be careful to avoid contact.
-Observe appropriate safety measures during operation, such as wearing appropriate protective equipment (gloves, goggles, etc.).
-Should be stored in a dry, cool place and avoid contact with oxidants and acids.
-When handling this compound, follow local regulations and safe practices.
Last Update：2024-04-09 20:49:11
