Benzoic acid, 4-bromo-3-hydroxy-

Benzoic acid, 4-bromo-3-hydroxy- - Names and Identifiers

Name	4-BROMO-3-HYDROXYBENZOIC ACID
Synonyms	2-Bromo-5-carboxyphenol 3-Hydroxy-4-broMobenzoicacid 4-BROMO-3-HYDROXYBENZOIC ACID Benzoic acid, 4-bromo-3-hydroxy-
CAS	14348-38-0
InChI	InChI=1/C7H5BrO3/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,9H,(H,10,11)

Benzoic acid, 4-bromo-3-hydroxy- - Physico-chemical Properties

Molecular Formula	C7H5BrO3
Molar Mass	217.02
Density	1.861±0.06 g/cm3(Predicted)
Melting Point	225-227
Boling Point	338.6±32.0 °C(Predicted)
Flash Point	158.6°C
Vapor Presure	3.77E-05mmHg at 25°C
Appearance	Crystallization
pKa	3.85±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.654
MDL	MFCD08056371
Physical and Chemical Properties	Storage Conditions: Keep Cold
In vitro study	IC50: 1 mM (Rat fetal histidine decarboxylase (HDC)), 1 mM (Ratgastric HDC), 1 mM (Hog kidney aromatic-L-amino acid decarboxylase), 1 mM (Rat gastric mucosa aromatic-L-amino acid decarboxylase)

Benzoic acid, 4-bromo-3-hydroxy- - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant/Keep Cold

Benzoic acid, 4-bromo-3-hydroxy- - Reference Information

biological activity

4-Bromo-3-hydroxybenzoic acid is a Brocresine metabolite and a histidine decarboxylase (HDC) inhibitor. The IC50 of HDC in rat fetuses and rats is 1 mM. 4-Bromo-3-hydroxybenzoic acid can also inhibit aromatic L-amino acid decarboxylase (aromatic-L-amino acid decarboxylase) in pig kidney and rat gastric mucosa in vitro, and the IC50 of both enzymes is 1 mM.

Last Update：2024-04-09 20:45:29