Benzonitrile, 3,5-difluoro-4-formyl-
3,5-二氟-4-甲酰苯甲腈
CAS: 467442-15-5
Molecular Formula: C8H3F2NO
Benzonitrile, 3,5-difluoro-4-formyl- - Names and Identifiers
| Name | 3,5-二氟-4-甲酰苯甲腈 |
| Synonyms | Benzonitrile, 3,5-difluoro-4-formyl- 3,5-Difluoro-4-forMylbenzonitrile[4-Cyano-2,6-difluorobenzaldehyde] |
| CAS | 467442-15-5 |
Benzonitrile, 3,5-difluoro-4-formyl- - Physico-chemical Properties
| Molecular Formula | C8H3F2NO |
| Molar Mass | 167.11 |
| Density | 1.35±0.1 g/cm3(Predicted) |
| Melting Point | 97-101°C |
| Boling Point | 261.9±40.0 °C(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Benzonitrile, 3,5-difluoro-4-formyl- - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
Benzonitrile, 3,5-difluoro-4-formyl- - Introduction
3,5-difluoro-4-formylbenzonitrile is an organic compound whose chemical formula is C9H5F2N. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless or yellowish crystal
-melting point: 78-80 ℃
-boiling point: 247-248 ℃
-Density: 1.38g/cm³
-Solubility: Soluble in organic solvents such as ethanol and dichloromethane
Use:
-3,5-difluoro-4-formylbenzonitrile is commonly used as an intermediate in organic synthesis for the synthesis of compounds and drugs.
-It can be used to prepare a variety of heterocyclic compounds and has important application value.
Preparation Method:
3,5-Difluoro-4-formylbenzonitrile can be prepared by the following method:
-First, p-benzoic acid pentafluoride is prepared by reacting p-benzoic acid with tin pentafluoride.
-Then, p-benzoic acid pentafluoride is reacted with nitrous acid to form p-benzoyl fluoride.
-Finally, the benzoyl fluoride and carbonitrile are reacted under alkaline conditions to prepare 3,5-difluoro-4-formylbenzonitrile.
Safety Information:
-3,5-Difluoro-4-formylbenzonitrile is an organic compound and care should be taken to avoid contact with skin, eyes and inhalation of its dust or vapors.
-Wear appropriate personal protective equipment such as chemical protective gloves, safety glasses and protective masks during handling.
-If you come into contact with this compound, rinse the affected area immediately with plenty of water and seek medical help.
Nature:
-Appearance: colorless or yellowish crystal
-melting point: 78-80 ℃
-boiling point: 247-248 ℃
-Density: 1.38g/cm³
-Solubility: Soluble in organic solvents such as ethanol and dichloromethane
Use:
-3,5-difluoro-4-formylbenzonitrile is commonly used as an intermediate in organic synthesis for the synthesis of compounds and drugs.
-It can be used to prepare a variety of heterocyclic compounds and has important application value.
Preparation Method:
3,5-Difluoro-4-formylbenzonitrile can be prepared by the following method:
-First, p-benzoic acid pentafluoride is prepared by reacting p-benzoic acid with tin pentafluoride.
-Then, p-benzoic acid pentafluoride is reacted with nitrous acid to form p-benzoyl fluoride.
-Finally, the benzoyl fluoride and carbonitrile are reacted under alkaline conditions to prepare 3,5-difluoro-4-formylbenzonitrile.
Safety Information:
-3,5-Difluoro-4-formylbenzonitrile is an organic compound and care should be taken to avoid contact with skin, eyes and inhalation of its dust or vapors.
-Wear appropriate personal protective equipment such as chemical protective gloves, safety glasses and protective masks during handling.
-If you come into contact with this compound, rinse the affected area immediately with plenty of water and seek medical help.
Last Update：2024-04-09 21:01:54
