Betamethasone 21-ace

Name	betamethasone 21-acetate
Synonyms	Betamethasone 21-ace Betamethasone Acetate betamethasone 21-acetate Betamethasone Acetate (500 mg) BETAMETHASONE ACETATE LINIMENTS 21-Acetyloxy-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione (17R)-16β-Methyl-21-acetoxy-11β,17α-dihydroxy-9α-fluoropregna-1,4-diene-3,20-dione (11β,16β)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-16-Methylpregna-1,4-diene-3,20-dione 9alpha-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-acetate (11beta,16beta)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate 9ALPHA-FLUORO-16BETA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 21-ACETATE (8xi,10xi,11beta,13xi,16beta)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate
CAS	987-24-6
EINECS	213-578-6
InChI	InChI=1/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1

Molecular Formula	C24H31FO6
Molar Mass	434.5
Density	1.0932 (rough estimate)
Melting Point	200-220°C (dec.)
Boling Point	579.4±50.0 °C(Predicted)
Specific Rotation(α)	D +140° (chloroform)
Flash Point	304.2°C
Water Solubility	30mg/L(25 ºC)
Solubility	Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent) and in methylene chloride. It shows polymorphism (5.9).
Vapor Presure	7.75E-16mmHg at 25°C
Appearance	neat
Color	White to Off-White
Merck	14,1180
pKa	12.08±0.70(Predicted)
Storage Condition	Refrigerator
Refractive Index	1.5980 (estimate)
Physical and Chemical Properties	Melting Point: 200-220°C (dec.) Merck:1180

Hazard Symbols	Xn - Harmful
Risk Codes	40 - Limited evidence of a carcinogenic effect
Safety Description	S22 - Do not breathe dust. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	2937220000