Name | Glucosamine sulfate |
Synonyms | Einecs 239-088-2 Glucosamine sulfate Glucosamine sulfate salt D-GLUCOSAMINE SULFATE 2KCL Glucosamine Sulphate 2KHCL D-Glucosamine potassium sulfate D-GLUCOSAMINESULFATE(K+)POTASSIUM Bis(2-ammonio-2-deoxy-D-glucose) sulphate |
CAS | 14999-43-0 |
EINECS | 239-088-2 |
InChI | InChI=1/2C6H13NO5.H2O4S/c2*7-3(1-8)5(11)6(12)4(10)2-9;1-5(2,3)4/h2*1,3-6,9-12H,2,7H2;(H2,1,2,3,4)/t2*3-,4+,5+,6+;/m00./s1 |
Molecular Formula | 2C6H13NO5.H2O4S |
Molar Mass | 456.42 |
Melting Point | 176°C |
Boling Point | 961.9°C at 760 mmHg |
Flash Point | 535.5°C |
Solubility | Water:55 mg/mL (198.37 mM);DMSO:4 mg/mL (14.42 mM) |
Vapor Presure | 0mmHg at 25°C |
Appearance | White crystal |
Storage Condition | Sealed in dry,Room Temperature |
MDL | MFCD00080790 |
Reference Show more | 1. Huang Xiuli, Weng Jia, Zhang Fengyun, Wang Xiaoqin, Wen Xiaoyu, Lin Fengping, Chen Wencai. Determination of Glucosamine Compounds in Health Food [J]. Food Science and Technology, 2020,45(10):289-294. |
introduction | D-glucosamine sulfate was first collected in the 27th edition of the us pharmacopoeia and is a drug for the treatment of arthritis. Arthritis has become the number one disabling disease in the world. With the aggravation of arthritis pain and obstruction of activities, it will lead to temporary or permanent incapacity. Due to its high activity and easy absorption, D-glucosamine sulfate is the main matrix of articular cartilage and articular fluid, and is more and more widely used in the treatment of arthritis. |
detection method | (1) dissolution: D-glucosamine sulfate is taken and dissolved in a solvent at 0 ℃; The solvent is saturated ammonium sulfate solution or dimethyl sulfoxide; The weight-volume ratio of D-glucosamine sulfate to solvent is 100mg:1ml; The solution is filtered to obtain a solid;(2) Detection: according to the detection method of potassium chloride (or sodium chloride) and potassium sulfate (or sodium sulfate), the obtained solid is used to detect chloride ions and sulfate ions; the detection methods of chloride ions and sulfate ions are all in accordance with the "Chinese Pharmacopoeia" 2010 edition, Part II Appendix VIII A Chloride Inspection Method, Appendix VIII B Sulfate Inspection Method;(3) Determination: Through the above detection results of chloride ions and sulfate ions, the D-glucosamine sulfate prepared by different methods is distinguished; in saturated ammonium sulfate solution, the completely dissolved is D-glucosamine sulfate potassium chloride salt or D-glucosamine sulfate sodium chloride salt, there is an insoluble substance and is potassium sulfate, the original substance is D-glucosamine hydrochloride potassium sulfate mixture, there is an insoluble substance and is sodium sulfate, the original substance is D-glucosamine hydrochloride sodium sulfate mixture; dissolved in dimethyl sulfoxide, the insoluble substance is potassium chloride, and the original substance is D-glucosamine sulfate potassium chloride; the insoluble substance is sodium chloride, and the original substance is D-glucosamine sulfate sodium chloride salt; Dissolved in dimethyl sulfoxide, the insoluble substance is potassium sulfate, and the original substance is D-glucosamine hydrochloride potassium sulfate mixture; the insoluble substance is sodium sulfate, and the original substance is D-glucosamine hydrochloride sodium sulfate mixture. |
application | D-glucosamine sulfate is a white crystalline powder with no smell and slightly salty taste. Easily soluble in water, slightly soluble in methanol, insoluble in organic solvents such as ethanol. Used as raw materials for medicine. |