overview | argyi oil is a volatile oil distilled from dried leaves or fresh leaves of Artemisia argyi Levl.et Vant.). the main components are terpene alcohol -4 and α-terpene alcohol. together with other components of this product, it can directly relax bronchial smooth muscle, to antigen, acetylcholine, histamine-induced bronchial smooth muscle spastic asthma. In addition, it has anti-allergic effect, which can inhibit the slow reaction substance (SRS-A) released by sensitized lungs, and has the effect of antagonizing SRS-A and serotonin. There are also certain expectorant and antitussive effects. No side effects of exciting the heart. Used for bronchial asthma, wheezing bronchitis and other bronchospastic diseases. |
extract | [source] dried leaves of argyi iévl. et Vant., a Compositae plant, Artemisia. [Habitat distribution] Born on roadsides, grasslands, wilderness, etc., and also cultivated. Most areas of China are distributed, mainly producing Shandong, Anhui, Hubei, Hunan and other places. [Plant Morphology] Perennial herb, 20 ~ 100cm high. The stem is erect, single, with longitudinal ribs, often purplish brown, densely covered with off-white spider silk hairs. The middle leaf has a short stalk or a slightly longer stalk, the stalk base is slightly expanded, the leaf blade is 1~2 pinnately deeply or completely split, the lateral lobes are 2~3 pairs, the lobes are elliptic or lanceolate, the edges are coarsely serrated or small lobes, the upper part is sparsely covered with spider-like hairs, densely covered with glandular dots; the lower part is densely covered with gray-white or gray-yellow spider-like hairs or felt hairs, the upper leaves are gradually small, 3~5 divided or undivided, lobes lanceolate or stripe-lanceolate, sessile. The flower head is bell-shaped or rectangular bell-shaped, most of which are arranged in a compact and slightly expanded cone shape at the end of the branch, with 4-5 layers of involucre, densely covered with gray-white or gray-yellow spider-like hairs, with small marginal flowers female, 8-13 pieces, corolla narrow tubular cone, central florets bisexual, 9-11 pieces, corolla tubular bell-shaped, reddish purple. Achenes are oblong. Flowering period is from August to September and fruiting period is from September to October. Sex and taste return to the classics: bitter, pungent, warm; poisonous. Return to liver, spleen and kidney meridian. Fig. 1 shows the chemical components of mugwort leaf extracted from mugwort leaf oil. the main types are monoterpenes, sesquiterpenes and their derivatives, of which 1, 8-eucalyptol, terpineol, spearol, caryophyllene oxide and juniper camphor are the main components, accounting for about 40% of the total, and borneol, mauranene and camphor account for about 10% of the total. The composition and content of wormwood leaf oil vary with the variety, growth climate and soil environment of wormwood leaf. |
extraction method | 1. steam distillation method: this method has a long extraction process, high temperature and open system, which is easy to cause thermal instability, damage and volatilization loss of easily oxidized components. 2. Supercritical CO2 fluid extraction method: components with lower polarity can be extracted, and components with large molecular weight are relatively large. |
pharmacological action | 1. antiallergic effect mugwort oil has obvious protective effect on anaphylactic shock in guinea pigs, but spray administration is ineffective. 2. Sedative effect Artemisia vulgaris oil has a sedative effect on the central nervous system and can reduce the activity of rabbits. Ingavage of mice can significantly prolong the sleep time of pentobarbital sodium. 3. Effect on the heart In vitro toad heart and rabbit heart experiments, mugwort oil can inhibit myocardial contractility, but does not affect heart rate and coronary flow. 4. The effect of invigorating the stomach and promoting gallbladder can promote the secretion of gastric juice. Oral administration of mugwort can increase appetite, but a large number of counter-reactions can cause nausea and vomiting. Artemisia vulgaris oil has obvious choleretic effect on carbon tetrachloride poisoning rats and mice. 0.8 ml/100g of mugwort oil suspension increased bile flow by 91.59% in normal rats. 5. Anti-asthmatic effect Artemisia vulgaris oil has anti-asthmatic effect on guinea pig drug-induced asthma, and its intensity is similar to that of isoproterenol (0.5 mg/ml); it has relaxation effect on guinea pig isolated trachea, and has anti-histamine-induced bronchoconstriction effect. Terpene alcohol -4 and α terpene alcohol have stronger antiasthmatic effects in the whole and in vitro than Artemisia muga oil. When α-terpene alcohol relaxes the concentration of tracheal smooth muscle (10-4g/ml), the cAMP content of guinea pig tracheal smooth muscle can be significantly increased, which may be the biochemical mechanism of its relaxation of tracheal smooth muscle. 6. Antitussive effect Artemisia vulgaris oil has obvious antitussive effect on cough caused by acrolein or citric acid in guinea pigs. 7. expectorant effect Phenol red method showed that mice oral or intraperitoneal injection of mugwort oil had expectorant effect. 8. Antimicrobial effect of mugwort oil in vitro test, against pneumococcus, Staphylococcus aureus, Streptococcus A, Neisseria, Escherichia coli, Typhoid bacillus, paratyphoid bacillus, Shigella flexneri, Proteus, etc., All have inhibitory effects, the lowest inhibitory concentration is 2 × 10-3~4 × 10-3 ml/ml broth. |
application | 1. for the treatment of bronchospastic diseases such as bronchial asthma and asthmatic bronchitis. 2. As a natural antibacterial agent, it is mainly used in the treatment of sores, skin fungal infections, respiratory infections, etc. In addition, it can also be used as a raw material for medical and health care drugs and daily chemical products. 3. It can be used as a disinfectant for air. 4. As a fungicide for fabrics, it is used as a raw material for preparing masks. 5. Can be used for whitening skin care products. The overview, extraction methods, pharmacological effects and applications of Artemisia vulgis oil are edited by Ding Hong. (2015-11-23) |
Attention and taboos | A few people may have dry throat, nausea, and upper abdominal discomfort, which can disappear by themselves. |