Boc-3-amino-2-hydroxypropionic acid

Boc-3-amino-2-hydroxypropionic acid - Names and Identifiers

Name	3-[(tert-butoxycarbonyl)amino]-2-hydroxypropanoic-3-6-5(1)8\|h1-2,6H,3-4H2
Synonyms	Boc-3-aMino-2-hydroxypropionic acid N-β-(t-Butoxycarbonyl)-DL-isoserine Boc-3-amino-2-hydroxypropionic acid 3-(BOC-AMINO)-2-HYDROXYPROPANOIC ACID 3-(tert-Butoxycarbonylamino)-2-hydroxypropanoic acid Propanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy- Propanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy- (9CI)
CAS	218916-64-4
InChI	C

Boc-3-amino-2-hydroxypropionic acid - Physico-chemical Properties

Molecular Formula	C8H15NO5
Molar Mass	205.21
Density	1.24g/cm³
Boling Point	391.742°C at 760 mmHg
Flash Point	190.719°C
Vapor Presure	0mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.486

Boc-3-amino-2-hydroxypropionic acid - Introduction

3-[(tert-butoxycarbonyl)amino]-2-hydroxypropanoic-3-6-5(1)8 | h1-2,6h, 3-4H2 is an organic compound with the chemical formula C9H17NO5. Its properties are as follows:

1. Appearance: 3-[(tert-butoxycarbonyl)amino]-2-hydroxypropanoic-3-6-5(1)8 | h1-2,6h, 3-4H2 is usually a white crystalline solid.
2. Solubility: It has low solubility in water and is soluble in organic solvents such as chloroform, dimethyl sulfoxide, etc.
3. Chemical properties: The compound is stable and not easy to decompose or react.

3-[(tert-butoxycarbonyl)amino]-2-hydroxypropanoic-3-6-5(1)8 | h1-2,6h, 3-4H2 are mainly used in the following aspects:

1. Pharmaceutical field: as a protective group, commonly used in the synthesis of drugs and peptide compounds. It can temporarily protect amino and hydroxyl groups to prevent undesired side reactions in chemical reactions.
2. Biochemical research: used for the synthesis and study of peptides, proteins and peptides compounds.

3-[(tert-butoxycarbonyl)amino]-2-hydroxypropanoic-3-6-5(1)8 | h1-2,6h, 3-4H2 are generally prepared in two common ways:

1. Boc protection: 3-amino-2-hydroxypropionic acid is reacted with tert-butoxycarbonamide to produce 3-[(tert-butoxycarbonyl)amino]-2-hydroxypropanoic-3-6-5(1)8 | h1-2,6h, 3-4H2.
2. Deacidification protection method: remove the methoxy group from the existing 3-methoxy -2-hydroxy propionic acid by acid treatment, and then react with tert-butoxycarbonyl amide to generate 3-[(tert-butoxycarbonyl)amino]-2-hydroxypropanoic-3-6-5(1)8 | h1-2,6h, 3-4H2.

Safety information about 3-[(tert-butoxycarbonyl)amino]-2-hydroxypropanoic-3-6-5(1)8 | h1-2,6h, 3-4H2, due to its low toxicity, it is generally believed that there is no obvious harm to human body under normal operation and storage conditions. However, any chemical should be used with caution and in strict compliance with safe practices to avoid contact with dust and liquids of the compound into the eyes, inhalation or ingestion. In the case of accidental contact or ingestion, medical assistance should be sought immediately.

Last Update：2024-04-10 22:41:56