Boc-Met(O)-OH - Names and Identifiers
Name | Boc-Met(O)-OH
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Synonyms | BOC-L-MET(O) BOC-MET(O)-OH Boc-Met(O)-OH BOC-L-MET(O)-OH BOC-L-METHIONINE (O) BOC-L-METHIONINE SULFOXIDE Boc-L-methionine sulfoxide N-ALPHA-T-BOC-L-METHIONINE-D,L-SULFOXIDE N-ALPHA-T-BUTOXYCARBONYL-L-METHIONINE SULFOXIDE N-ALPHA-TERT-BUTYLOXYCARBONYL-L-METHIONINESULFOXIDE (2S)-2-[(tert-Butoxycarbonyl)amino]-4-(methylsulfinyl)butanoic acid Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-(methylsulfinyl)-, (2S)-
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CAS | 34805-21-5
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InChI | InChI=1/C10H19NO5S/c1-10(2,3)16-9(14)11-7(8(12)13)5-6-17(4)15/h7H,5-6H2,1-4H3,(H,11,14)(H,12,13)/t7-,17?/m0/s1 |
Boc-Met(O)-OH - Physico-chemical Properties
Molecular Formula | C10H19NO5S
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Molar Mass | 265.33 |
Density | 1.260±0.06 g/cm3(Predicted) |
Boling Point | 509.3±45.0 °C(Predicted) |
Flash Point | 261.8°C |
Vapor Presure | 9.48E-12mmHg at 25°C |
Appearance | Solid |
pKa | 3.70±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
Refractive Index | 1.521 |
Boc-Met(O)-OH - Risk and Safety
WGK Germany | WGK 2 water endanger |
HS Code | 2930 90 98 |
Boc-Met(O)-OH - Introduction
Boc-Met(O)-OH(Boc-Met(O)-OH) is an organic compound that contains a butoxycarbonyl (Boc) protecting group and methionine in its structure.
Nature:
-Appearance: Common form is white crystal or powder.
-Solubility: Soluble in some organic solvents (such as methanol, dimethylformamide), but insoluble in water and weak acidic conditions.
Use:
- Boc-Met(O)-OH is often used as an intermediate in drug synthesis. As a protecting group, the active group that can protect methionine is protected during the synthesis.
-It can also be used to synthesize peptides and proteins as a protecting group for amino acids.
Preparation Method:
the common synthesis method is to first react methionine with some activator of butoxycarbonyl acid (such as DCC), and then remove the protecting group under appropriate conditions to obtain Boc-Met(O)-OH.
Safety Information:
- Boc-Met(O)-OH has no special safety risk under routine use, but as an organic compound, it may cause certain irritation and toxicity to the human body.
-During handling and use, appropriate personal protective measures are required, such as wearing gloves and safety glasses, and maintaining well-ventilated laboratory conditions.
Last Update:2024-04-09 02:00:45