Bromo(4-cyanophenyl) zinc
4-CYANOPHENYLZINC BROMIDE
CAS: 131379-14-1
Molecular Formula: C7H4BrNZn
Bromo(4-cyanophenyl) zinc - Names and Identifiers
| Name | 4-CYANOPHENYLZINC BROMIDE |
| Synonyms | (p-Cyanophenyl)bromozinc Bromo(4-cyanophenyl) zinc 4-CYANOPHENYLZINC BROMIDE 4-(Bromozincio)benzonitrile (4-cyanophenyl)zinc(II) broMide 4-Cyanophenylzinc bromide solution 0.5 in THF 4-Cyanophenylzinc bromide solution 0.5M in THF 4-Cyanophenylzinc bromide, Packaged under Argon in resealable ChemSeal? bottles |
| CAS | 131379-14-1 |
| InChI | InChI=1/C7H4N.BrH.Zn/c8-6-7-4-2-1-3-5-7;;/h2-5H;1H;/q;;+1/p-1/rC7H4BrNZn/c8-10-7-3-1-6(5-9)2-4-7/h1-4H |
Bromo(4-cyanophenyl) zinc - Physico-chemical Properties
| Molecular Formula | C7H4BrNZn |
| Molar Mass | 247.41 |
| Density | 0.98g/mLat 25°C |
| Flash Point | 1°F |
| Water Solubility | Reacts with water. |
| Exposure Limit | ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)OSHA: TWA 200 ppm(590 mg/m3)NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) |
| Storage Condition | 2-8°C |
| Sensitive | Air Sensitive |
| Physical and Chemical Properties | WGK Germany:1 |
Bromo(4-cyanophenyl) zinc - Risk and Safety
| Risk Codes | R19 - May form explosive peroxides R22 - Harmful if swallowed R36/38 - Irritating to eyes and skin. R40 - Limited evidence of a carcinogenic effect R36/37 - Irritating to eyes and respiratory system. R14 - Reacts violently with water R11 - Highly Flammable |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S33 - Take precautionary measures against static discharges. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 3399 4.3/PG 2 |
| WGK Germany | 1 |
| Hazard Class | 4.3 |
Bromo(4-cyanophenyl) zinc - Introduction
4-cyanophenyl zinc bromide is an organic compound with the chemical formula C6H4CBrN · ZnBr2. Next, its nature, use, preparation and safety information will be introduced respectively.
Nature:
4-Cyanophenyl Zinc Bromide is a colorless crystalline solid that is stable at room temperature. It has good solubility properties and can be dissolved in organic solvents, such as ethanol and dimethylformamide. In addition, it is also an effective organometallic reagent and can be used in organic synthesis reactions.
Use:
4-cyanophenyl zinc bromide is widely used in organic synthesis. It is often used as a reagent for palladium-catalyzed cross-coupling reactions, allowing it to bond with other organics. In addition, it can also be used to prepare other organometallic reagents and complexes.
Preparation Method:
The preparation of 4-cyanophenylzinc bromide is usually obtained by reacting 4-bromophenylcyanide bromide and zinc bromide in an anhydrous solvent. During the reaction, attention should be paid to the operating conditions and reaction time to ensure the quality of the product.
Safety Information:
When operating 4-cyanophenyl zinc bromide, you need to pay attention to safety measures. It is an organometallic reagent with certain toxicity and may cause irritation and damage to the human body. Wear safety glasses, gloves and lab clothes during operation and in a well-ventilated environment. Avoid inhaling its dust or contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help. In addition, the storage should be sealed, away from the fire and oxidant.
Nature:
4-Cyanophenyl Zinc Bromide is a colorless crystalline solid that is stable at room temperature. It has good solubility properties and can be dissolved in organic solvents, such as ethanol and dimethylformamide. In addition, it is also an effective organometallic reagent and can be used in organic synthesis reactions.
Use:
4-cyanophenyl zinc bromide is widely used in organic synthesis. It is often used as a reagent for palladium-catalyzed cross-coupling reactions, allowing it to bond with other organics. In addition, it can also be used to prepare other organometallic reagents and complexes.
Preparation Method:
The preparation of 4-cyanophenylzinc bromide is usually obtained by reacting 4-bromophenylcyanide bromide and zinc bromide in an anhydrous solvent. During the reaction, attention should be paid to the operating conditions and reaction time to ensure the quality of the product.
Safety Information:
When operating 4-cyanophenyl zinc bromide, you need to pay attention to safety measures. It is an organometallic reagent with certain toxicity and may cause irritation and damage to the human body. Wear safety glasses, gloves and lab clothes during operation and in a well-ventilated environment. Avoid inhaling its dust or contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help. In addition, the storage should be sealed, away from the fire and oxidant.
Last Update：2024-04-10 22:29:15
