Name | Bromocresol Purple |
Synonyms | BCP Bromcresol Purple Bromocresol Purple dibromo-o-cresolsulphonephthalein 5,5-Dibromo-o-cresolsulfonephthalein 3',3''-DIBROMO-O-CRESOLSULFONPHTHALEIN Bromocresol Purple, indicator grade, pure Bromocresol purple indicator solution (for microbial limit check) 4,4'-(3h-2,1-benzoxathiol-3-ylidene)bis(2-bromo-6-o-cresol)s,s-dioxide 4,4'-(3H-2,1-Benzoxathiol-3-ylidene)bis[2-bromo-b-methylphend]S,S-dioxide 4,4'-(3h-2,1-benzoxathiol-3-ylidene)bis(2-bromo-6-methylphenol)s,s-dioxide 4,4'-(1,1-dioxido-3H-2,1-benzoxathiole-3,3-diyl)bis(2-bromo-6-methylphenol) Phenol, 4,4-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis2-bromo-6-methyl- |
CAS | 115-40-2 |
EINECS | 204-087-8 |
InChI | InChI=1/C21H16Br2O5S/c1-11-7-13(9-16(22)19(11)24)21(14-8-12(2)20(25)17(23)10-14)15-5-3-4-6-18(15)29(26,27)28-21/h3-10,24-25H,1-2H3 |
InChIKey | ABIUHPWEYMSGSR-UHFFFAOYSA-N |
Molecular Formula | C21H16Br2O5S |
Molar Mass | 540.22 |
Density | 1.6509 (estimate) |
Melting Point | 240 °C (dec.) (lit.) |
Boling Point | 590.2±50.0 °C(Predicted) |
Flash Point | 36°C |
Water Solubility | practically insoluble |
Solubility | Soluble in ethanol and dilute alkali solution, almost insoluble in water |
Vapor Presure | 1.59E-14mmHg at 25°C |
Appearance | Bright yellow crystalline powder |
Color | Purplish-brown |
Maximum wavelength(λmax) | ['419nm, 433nm, 591nm'] |
Merck | 14,1387 |
BRN | 359618 |
pKa | 6.21, 6.3, 6.4(at 25℃) |
PH | pH : 5.2~6.8 |
Storage Condition | Store at +5°C to +30°C. |
Stability | Stable. Incompatible with strong oxidizing agents. |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.694 |
MDL | MFCD00011681 |
Physical and Chemical Properties | Slightly yellowish rose-colored crystalline powder. Insoluble in water, soluble in ethanol is yellow, soluble in dilute sodium hydroxide and dilute sodium carbonate solution is purple, melting point of 241-242 ℃. |
Use | Used as acid-base indicator and non-aqueous titration indicator |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R10 - Flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection S16 - Keep away from sources of ignition. |
UN IDs | UN 1993 3/PG 3 |
WGK Germany | 3 |
TSCA | Yes |
HS Code | 29349990 |
pH indicator color change ph range | 5.2(yellow)-6.8 (special) |
main applications | Waveguides, fuel cells, sensors, sol-gel technology, display device, falsification-proof security paper, paints, detergents, identifying fresh and stale rice, detecting lactic acid bacteria, Dental materials, vaginal infection test method |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
use | acid-base indicator, the color changes from light yellow to purple red, and the pH value of the color change range is 5.2-6.8. The main use of bromocresol purple acid-base indicator, non-aqueous titration indicator. Used as acid-base indicator and non-aqueous titration indicator Acid-base indicator, chromatographic analysis, non-aqueous titration indicator. pH color change range: 5.2 (yellow)-6.8 (purple). Adsorption indicator. Amino acid chromatography internal standard. Silver salt titration of thiocyanate. Spectrophotometric precipitation of serum proteins. |
production method | dissolve o-toluidine in dilute sulfuric acid, cool, add sodium nitrite solution under stirring, and control the reaction temperature below 5 ℃. After the reaction, heat to 40-50 ℃ until no bubbles occur, cool and filter, and fractionate o-cresol. O-cresol is mixed with o-toluenesulfonic anhydride and chloroform zinc, stirred and heated, reacted at 115-120 ℃ for 7h, removed the remaining o-cresol by steam, and filtered to obtain o-cresol red: o-cresol red is refined and dissolved in glacial acetic acid, mixed solution of bromine and glacial acetic acid is added under stirring, heated at 40-50 ℃ for 4h, cooled and filtered to obtain bromocresol purple. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |