CHOLINE BITARTRATE COATED
choline bitartrate
CAS: 87-67-2
Molecular Formula: C9H19NO7
CHOLINE BITARTRATE COATED - Names and Identifiers
| Name | choline bitartrate |
| Synonyms | Cholinebitartrate CHOLINE BITARTRATE choline bitartrate Cholini Bitatratis CHOLINE BITARTRATE SALT CHOLINE BITARTRATE COATED CHOLINE HYDROGEN TARTRATE choline hydrogen tartrate CHOLINE BITARTRATE UNCOATED 2-hydroxy-N,N,N-trimethylethanaminium 3-carboxy-2,3-dihydroxypropanoate 2-Hydroxyethyl-trimethylazanium (2R,3R)-2,3,4-trihydroxy-4-oxobutanoate 2-hydroxy-N,N,N-trimethylethanaminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate |
| CAS | 87-67-2 |
| EINECS | 201-763-4 |
| InChI | InChI=1/C5H14NO.C4H6O6/c1-6(2,3)4-5-7;5-1(3(7)8)2(6)4(9)10/h7H,4-5H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/q+1;/p-1 |
| InChIKey | QWJSAWXRUVVRLH-UHFFFAOYSA-M |
CHOLINE BITARTRATE COATED - Physico-chemical Properties
| Molecular Formula | C9H19NO7 |
| Molar Mass | 253.25 |
| Melting Point | 151-153°C |
| Boling Point | 399.3°C at 760 mmHg |
| Specific Rotation(α) | [α]D20 +15～+18° (c=4, H2O) |
| Flash Point | 209.4°C |
| Water Solubility | Soluble in alcohol and slightly soluble in water. |
| Solubility | DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly) |
| Vapor Presure | 4.93E-08mmHg at 25°C |
| Appearance | White crystalline powder |
| Color | White to Off-White |
| PH | 3.0-4.4 (50g/l, H2O, 20°C) |
| Storage Condition | Store at RT. |
| Sensitive | Hygroscopic |
| MDL | MFCD00036332 |
| Use | Vitamin B drugs for the treatment of hepatitis, early cirrhosis, pernicious anemia |
CHOLINE BITARTRATE COATED - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29231000 |
CHOLINE BITARTRATE COATED - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | choline [HOCH2CH2N(CH3)3]OH is a strong organic base, which is a component of lecithin, it is also found in sphingomyelin, a source of variable methyl groups in the body and acts on the product of the synthesis of methyl groups, while it is the precursor of acetylcholine, choline is heat resistant, and there is little loss during processing and cooking, in a dry environment, there is little change in the choline content of food even when stored for a long time. Choline is an important component of sphingomyelin, phosphatidylcholine, which is widely found in plants and animals. |
| principle of action | The main functions of choline are: 1 to promote brain development and improve memory ability; 2 to ensure information transmission; regulation of apoptosis 4 important components of biofilm 5 promoting fat metabolism 6 promoting methyl metabolism in vivo 7 lowering serum cholesterol. Choline is widely present in various foods, especially in liver, peanuts, and vegetables. A member of the B group of vitamins that are lipophilic vitamins (emulsifiable fats); Enemies of choline: water, sulfonamides, estrogens, food processing, alcohol. |
| preparation | choline bitartrate can be prepared from aqueous solutions of high concentrations of ethylene oxide, at room temperature and the role of trimethylamine to choline, so that dissolved in methanol, according to the molar value of the addition of tartaric acid neutralization, and then concentrated, dried, acetone recrystallization refined. |
| content analysis | accurately weigh a mg sample into a ML Erlenmeyer flask, after addition of 50ml of glacial acetic acid, it was heated on a steam bath until complete dissolution. After cooling, 2 drops of gentian violet reagent and 0.1mol/L perchloric acid glacial acetic acid solution were added dropwise to the green end point. At the same time, the blank test was carried out, and the necessary correction was made. Per mL of 0.1mol/L perchloric acid equivalent to this product (C9H19NO7)25.36mg. |
| toxicity | GRAS(FDA,§ 182.5250,§ 182.8250,2000). ADI is not limited (FAO/WHO,2001). |
| uses | vitamin B drugs for the treatment of hepatitis, early cirrhosis, pernicious anemia, etc, choline acetyltransferase substrate. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 20:45:29
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