CID 11210285 hydrochloride - Names and Identifiers
CID 11210285 hydrochloride - Physico-chemical Properties
Molecular Formula | C19H18N4O3
|
Molar Mass | 350.37 |
Density | 1.353±0.06 g/cm3(Predicted) |
Boling Point | 623.4±65.0 °C(Predicted) |
Solubility | DMSO: ≥ 30 mg/mL |
Appearance | Yellowish sticky solid |
Color | white to beige |
pKa | 6.62±0.10(Predicted) |
Storage Condition | 2-8°C |
In vitro study | BML-284 (10 µM; 24 hours) significantly increases the migration and invasion of both MNK45 and AGS cells and partially restores the migratory and invasive abilities of cells inhibited by pizotifen.BML-284 (10 µM; 24 hours) induces the expression of β-catenin significantly when compared with the NC group. It also partially reverses the effects induced by pizotifen on E-cadherin and N-cadherin expression in MNK45 and AGS cells compared with the pizotifen-treated group. Western Blot Analysis Cell Line: Human gastric cancer cell lines MNK45 and AGS [1] Concentration: 10 µM Incubation Time: 24 hours Result: Induced β-catenin expression and reserved E-cadherin and N-cadherin expression in MNK45 and AGS cells. |
In vivo study | BML-284 (10 ng) combines with Pyrimethanil (4 mg/L) could partially rescue the malformed phenotype and cardiac defects induced by Pyrimethanil in Tg (myl7:EGFP) transgenic embryos at 5.5 hpf are transferred into plates with 20 embryos. |
CID 11210285 hydrochloride - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/38 - Irritating to eyes and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
|
WGK Germany | 3 |
CID 11210285 hydrochloride - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.854 ml | 14.271 ml | 28.541 ml |
5 mM | 0.571 ml | 2.854 ml | 5.708 ml |
10 mM | 0.285 ml | 1.427 ml | 2.854 ml |
5 mM | 0.057 ml | 0.285 ml | 0.571 ml |
Last Update:2024-01-02 23:10:35