CIVENTICHEM CV-409
SU4984
CAS: 186610-89-9
Molecular Formula: C20H19N3O2
CIVENTICHEM CV-409 - Names and Identifiers
| Name | SU4984 |
| Synonyms | SU4984 CIVENTICHEM CV-409 |
| CAS | 186610-89-9 |
CIVENTICHEM CV-409 - Physico-chemical Properties
| Molecular Formula | C20H19N3O2 |
| Molar Mass | 333.38 |
| Solubility | Soluble in DMSO |
| Appearance | Orange to red crystalline solid. |
| Storage Condition | -20℃ |
| Use | SU4984 is a cell-permeable, reversible, and ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1 (FGFR1; IC50 = 10-20 µM). |
CIVENTICHEM CV-409 - Reference
| Reference Show more | 1: Matsuo M, Yamada S, Koizumi K, Sakurai H, Saiki I. Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells. Eur J Cancer. 2007 Jul;43(11):1748-54. Epub 2007 Jun 13. PubMed PMID: 17570654. 2: Mologni L, Sala E, Cazzaniga S, Rostagno R, Kuoni T, Puttini M, Bain J, Cleris L, Redaelli S, Riva B, Formelli F, Scapozza L, Gambacorti-Passerini C. Inhibition of RET tyrosine kinase by SU5416. J Mol Endocrinol. 2006 Oct;37(2):199-212. PubMed PMID: 17032739. 3: Welsh M, Welsh C, Ekman M, Dixelius J, Hägerkvist R, Annerén C, Akerblom B, Mahboobi S, Chandrasekharan S, Liu ET. The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity. Biochem J. 2004 Aug 15;382(Pt 1):261-8. PubMed PMID: 15186217; PubMed Central PMCID: PMC1133939. 4: Fuhrmann G, Leisser C, Rosenberger G, Grusch M, Huettenbrenner S, Halama T, Mosberger I, Sasgary S, Cerni C, Krupitza G. Cdc25A phosphatase suppresses apoptosis induced by serum deprivation. Oncogene. 2001 Jul 27;20(33):4542-53. PubMed PMID: 11494150. |
CIVENTICHEM CV-409 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3 ml | 14.998 ml | 29.996 ml |
| 5 mM | 0.6 ml | 3 ml | 5.999 ml |
| 10 mM | 0.3 ml | 1.5 ml | 3 ml |
| 5 mM | 0.06 ml | 0.3 ml | 0.6 ml |
Last Update：2024-01-02 23:10:35
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CAS: 186610-89-9
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 186610-89-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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