Ca2+ channel agonist 1
Ca2+ channel agonist 1
CAS: 1402821-24-2
Molecular Formula: C19H26N6O
Ca2+ channel agonist 1 - Names and Identifiers
| Name | Ca2+ channel agonist 1 |
| Synonyms | Ca2+ channel agonist 1 1-Butanol, 2-[[6-[(phenylmethyl)amino]-9-propyl-9H-purin-2-yl]amino]-, (2R)- |
| CAS | 1402821-24-2 |
Ca2+ channel agonist 1 - Physico-chemical Properties
| Molecular Formula | C19H26N6O |
| Molar Mass | 354.45 |
| Solubility | 10 mM in DMSO |
| Storage Condition | -20℃ |
| In vitro study | Ca 2+ channel agonist 1 (Compound 13d) is an agonist of N-type Ca 2+ channel and an inhibitor of Cdk2, with EC 50 s of 14.23 μM and 3.34 μM, respectively. Ca 2+ channel agonist 1 exhibits a ca. 2-fold increased agonism and a 22-fold decreased cdk2 kinase activity versus the standard, (R)-roscovitine. |
Ca2+ channel agonist 1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.821 ml | 14.106 ml | 28.213 ml |
| 5 mM | 0.564 ml | 2.821 ml | 5.643 ml |
| 10 mM | 0.282 ml | 1.411 ml | 2.821 ml |
| 5 mM | 0.056 ml | 0.282 ml | 0.564 ml |
Last Update：2024-01-02 23:10:35
Ca2+ channel agonist 1 - Reference Information
| biological activity | Ca2 channel agnist 1 is an N-type calcium channel (N-type Ca2 channel) agonists and inhibitors of Cdk2, with EC50 of 14.23 μm and 3.34 μm, respectively, have potential effects on motor nerve terminal dysfunction. |
Last Update：2024-04-09 21:50:46
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