Candesartan ester intermediate C4
Ethyl(2-ethoxy-1-benzimidazole)-7-carboxylate
CAS: 136285-67-1
Molecular Formula: C23H19N3O4
Candesartan ester intermediate C4 - Names and Identifiers
| Name | Ethyl(2-ethoxy-1-benzimidazole)-7-carboxylate |
| Synonyms | Candesartan ester intermediate C4 Ethyl(2-ethoxy-1-benzimidazole)-7-carboxylate ethyl 2-{[(2'-cyanobiphenyl-4-yl)methyl]amino}-3-nitrobenzoate Ethyl-2-[[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate Ethyl 2-[N-[(2'-Cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate Ethyl-2-[(2'-cyanobiphenyl-4-yl)Methyl aMino]-3-nitrobenzoate (C4) Ethyl 2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)-3-nitrobenzoate 2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester Benzoic acid,2-[[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-, ethyl ester 2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester |
| CAS | 136285-67-1 |
| EINECS | 603-952-0 |
| InChI | InChI=1/C23H19N3O4/c1-2-30-23(27)20-8-5-9-21(26(28)29)22(20)25-15-16-10-12-17(13-11-16)19-7-4-3-6-18(19)14-24/h3-13,25H,2,15H2,1H3 |
Candesartan ester intermediate C4 - Physico-chemical Properties
| Molecular Formula | C23H19N3O4 |
| Molar Mass | 401.41 |
| Density | 1.31 |
| Melting Point | >209°C (dec.) |
| Boling Point | 602.9±55.0 °C(Predicted) |
| Flash Point | 318.415°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Solid |
| Color | Yellow |
| pKa | -2.57±0.10(Predicted) |
| Storage Condition | Refrigerator |
| Refractive Index | 1.645 |
Candesartan ester intermediate C4 - Introduction
Ethyl 2-[[(2 '-cyanobiphenyl-4-yl) methyl] amino]-3-nitrobenzoate is an organic compound. The following is a description of some of its properties, uses, methods and safety information:
Nature:
-Chemical formula: C19H15N3O4
-Molecular weight: 349.34g/mol
-Appearance: White crystalline solid
-Melting point: 136-140 degrees Celsius
-Solubility: Insoluble in water, soluble in organic solvents such as ethanol and dimethylformamide
Use:
Ethyl 2-[[(2 '-cyanobiphenyl-4-yl) methyl] amino]-3-nitrobenzoate is commonly used as an important intermediate and raw material in organic synthesis
-It can be used to synthesize fluorescent dyes, pharmaceutical intermediates and other compounds
-Has certain application potential in pharmaceutical research, such as the development of anti-cancer drugs
Preparation Method:
-The preparation of ethyl 2-[[(2 '-cyanobiphenyl-4-yl) methyl] amino]-3-nitrobenzoate is usually achieved by chemical synthesis
-The specific preparation method varies with the experimental conditions and the choice of reactants. It generally involves the reaction of benzoyl chloride and 2-cyanobiphenol, followed by the condensation of ammonia and methanol, nitric acid and other reactions, and finally The target product is obtained
Safety Information:
- 2-[[(2 '-Cyanobiphenyl-4-yl) methyl] amino]-3-nitrobenzoic acid ethyl ester is an organic compound, which requires safe operation in the laboratory
-Follow relevant operating specifications and chemical safety measures during use
-It is a chemical that has certain toxicity and can cause irritation and damage to the eyes, skin and respiratory system
-Personal protective equipment such as goggles, gloves and masks must be worn during operation
-Avoid contact with oxidants and flammable substances, pay attention to fire and explosion-proof measures when storing, and keep away from children.
Nature:
-Chemical formula: C19H15N3O4
-Molecular weight: 349.34g/mol
-Appearance: White crystalline solid
-Melting point: 136-140 degrees Celsius
-Solubility: Insoluble in water, soluble in organic solvents such as ethanol and dimethylformamide
Use:
Ethyl 2-[[(2 '-cyanobiphenyl-4-yl) methyl] amino]-3-nitrobenzoate is commonly used as an important intermediate and raw material in organic synthesis
-It can be used to synthesize fluorescent dyes, pharmaceutical intermediates and other compounds
-Has certain application potential in pharmaceutical research, such as the development of anti-cancer drugs
Preparation Method:
-The preparation of ethyl 2-[[(2 '-cyanobiphenyl-4-yl) methyl] amino]-3-nitrobenzoate is usually achieved by chemical synthesis
-The specific preparation method varies with the experimental conditions and the choice of reactants. It generally involves the reaction of benzoyl chloride and 2-cyanobiphenol, followed by the condensation of ammonia and methanol, nitric acid and other reactions, and finally The target product is obtained
Safety Information:
- 2-[[(2 '-Cyanobiphenyl-4-yl) methyl] amino]-3-nitrobenzoic acid ethyl ester is an organic compound, which requires safe operation in the laboratory
-Follow relevant operating specifications and chemical safety measures during use
-It is a chemical that has certain toxicity and can cause irritation and damage to the eyes, skin and respiratory system
-Personal protective equipment such as goggles, gloves and masks must be worn during operation
-Avoid contact with oxidants and flammable substances, pay attention to fire and explosion-proof measures when storing, and keep away from children.
Last Update：2024-04-09 19:05:46
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Product Name: Azilsartan Impurity 23 Visit Supplier Webpage Request for quotationCAS: 136285-67-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
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Multiple Specifications
Product Name: 2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester Visit Supplier Webpage Request for quotationCAS: 136285-67-1
Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: 2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester Request for quotationCAS: 136285-67-1
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
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