Carbamohydroxamic acid
Hydroxyurea
CAS: 127-07-1
Molecular Formula: CH4N2O2
Carbamohydroxamic acid - Names and Identifiers
Carbamohydroxamic acid - Physico-chemical Properties
| Molecular Formula | CH4N2O2 |
| Molar Mass | 76.05 |
| Density | 1.457±0.06 g/cm3(Predicted) |
| Melting Point | 135-140°C |
| Boling Point | 136.04°C (rough estimate) |
| Water Solubility | soluble |
| Solubility | Soluble in water and hot ethanol, slightly soluble in cold ethanol, insoluble in ether; benzene. |
| Appearance | White powder |
| Color | white |
| Merck | 14,4848 |
| BRN | 1741548 |
| pKa | 10.56±0.23(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Stable for 2 years as supplied from date of purchase. Solutions in water may be stored at -20°C for up to 3 months. |
| Refractive Index | 1.4840 (estimate) |
| MDL | MFCD00007943 |
| Physical and Chemical Properties | Melting point 142-146°C water-soluble solution |
| Use | Anti-metabolic anticancer drugs, mainly acting on the G1 and S phase of proliferating cells, have a delaying effect on the G1/S interface, and are cell-specific drugs |
Carbamohydroxamic acid - Risk and Safety
| Risk Codes | R46 - May cause heritable genetic damage R63 - Possible risk of harm to the unborn child R61 - May cause harm to the unborn child R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 - Wear suitable protective clothing. S22 - Do not breathe dust. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| RTECS | YT4900000 |
| HS Code | 29242100 |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
| Packing Group | III |
Carbamohydroxamic acid - Reference
| Reference Show more | 1. Yang Tao. Establishment and Evaluation of Rat CKD Model of Kidney Yang Deficiency Induced by Adriamycin Combined with Hydroxyurea and Study on Intervention Mechanism of Zhenwu Decoction [D]. Beijing University of Traditional Chinese Medicine, 2020. |
Carbamohydroxamic acid - Introduction
This product is a nucleoside diphosphate reductase inhibitor, which can prevent the reduction of nucleotides to deoxynucleotides, interfere with purine and pyrimidine base biosynthesis, selectively hinder DNA synthesis, and have no blocking effect on RNA and protein synthesis. Cycle-specific drugs, S-phase cells are sensitive.
Last Update：2022-10-16 17:13:02
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Product Name: Hydroxyurea；Hydroxycarbamide；N-HYDROXYUREA Request for quotationCAS: 127-07-1
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
Spot supply
Product Name: Hydroxyurea Visit Supplier Webpage Request for quotationCAS: 127-07-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Hydroxyurea Request for quotation
CAS: 127-07-1
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302
Product List: View Catalog
CAS: 127-07-1
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302
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