Cbz-3,5-diiodo-L-tyrosine ethyl ester

Cbz-3,5-diiodo-L-tyrosine ethyl ester - Names and Identifiers

Name	Z-TYR(3,5-I2)-OET
Synonyms	Z-TYR(3,5-I2)-OET Z-3,5-DIIODO-TYR-OET Z-3,5-diiodo-L-Tyr-OEt Z-3,5-DIIODO-L-TYROSINE ETHYL ESTER Cbz-3,5-diiodo-L-tyrosine ethyl ester L-Tyrosine, 3,5-diiodo-N-[(phenylmethoxy)carbonyl]-, ethyl ester (S)-Ethyl 2-(((benzyloxy)carbonyl)amino)-3-(4-hydroxy-3,5-diiodophenyl)propanoate
CAS	102202-92-6

Cbz-3,5-diiodo-L-tyrosine ethyl ester - Physico-chemical Properties

Molecular Formula	C19H19I2NO5
Molar Mass	595.17
Density	1.835±0.06 g/cm3(Predicted)
Boling Point	575.1±50.0 °C(Predicted)
pKa	6.89±0.25(Predicted)

Cbz-3,5-diiodo-L-tyrosine ethyl ester - Introduction

Z-TYR(3,5-I2)-OET(Z-p-Iodine ethyl ester) is an organic compound whose chemical formula is C13H14I2N2O2. The following is a description of the nature, use, preparation and safety information of Z-TYR(3,5-I2)-OET:

Nature:
1. Appearance: White to light yellow solid.
2. Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM), slightly soluble in water.
3. Melting point: about 110-115°C.

Use:
1. Z-TYR(3,5-I2)-OET is a biologically active molecule, which is commonly used in chemical biology research, such as the design and development of drug molecules, protein structure and function research and other fields.
2. It can be used as a compound containing iodine atoms for labeling and tracking specific molecules or cells in organisms.

Preparation Method:
The preparation method of Z-TYR(3,5-I2)-OET is relatively complex and requires multi-step synthesis. A commonly used preparation method is to react p-iodobenzoic acid with p-tert-butylbenzoic acid to produce ethyl p-iodobenzoate, which is then reacted with an amino acid ester to finally obtain Z-TYR(3,5-I2)-OET.

Safety Information:
1. Z-TYR(3,5-I2)-OET is an organic compound with certain toxicity. Please wear appropriate personal protective equipment during operation to avoid direct skin contact.
2. Due to its organic structure and chemical properties, it may produce combustible gases at high temperatures and avoid contact with strong oxidants and combustibles.
3. When using or storing, please pay attention to avoid reaction with acid, alkali and other substances to avoid dangerous substances.
4. If inhaled or ingested by mistake, seek medical attention immediately and show the relevant chemical information to the doctor.

Last Update：2024-04-09 21:04:16