Cetirizine EP Impurity B DiHCl

Cetirizine EP Impurity B DiHCl - Names and Identifiers

Name	De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride
Synonyms	Cetirizine-3 Cetirizine Impurity B DiHCl Cetirizine EP Impurity B DiHCl Cetirizine Impurity B dihydrochloride De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride LEVOCETIRIZINE IMPURITY 3 DIHCL (CETIRIZINE EP IMPURITY B DIHCL) Cetirizine EP Impurity B DiHCl (Levocetirizine Impurity 3 DiHCl) Levocetirizine Impurity 3 DiHCl (Cetirizine EP Impurity B DiHCl) CETIRIZINE EP IMPURITY B DIHCL (LEVOCETIRIZINE IMPURITY 3 DIHCL) 2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic acid dihydrochloride
CAS	1000690-91-4

Cetirizine EP Impurity B DiHCl - Physico-chemical Properties

Molecular Formula	C19H22Cl2N2O2
Molar Mass	381.3
Melting Point	>168°C (dec.)
Solubility	DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Appearance	Solid
Color	White to Pale Beige
Storage Condition	Hygroscopic, -20°C Freezer, Under inert atmosphere

Cetirizine EP Impurity B DiHCl - Introduction

De(carboxymethoxy) Cetirizine Acid Dihydrochloride is an organic compound with the chemical name 1-[2-[(4-chlorine)(phenyl)methyl]benzimidazolium iodide. It is a common impurity of cetirizine (also known as chlorpheniramine, diphenhydramine).

The properties of De(carboxymethoxy) Cetirizine Acid Dihydrochloride include:
-Appearance: often white crystalline powder or crystal;
-Melting Point: about 170-172 ℃;
-Solubility: Soluble in solvents such as water, ethanol and chloroform.

De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride is mainly used as an impurity reference standard for the drug Cetirizine, which can be used for quality control and analysis of pharmaceutical preparations. It plays a key role in ensuring the quality of drugs in the pharmaceutical industry.

As for the preparation method, De(carboxymethoxy) Cetirizine Acid Dihydrochloride is usually obtained by chemical synthesis. Specific manufacturing methods may vary by manufacturer and supplier.

As for safety information, the toxicity and harmfulness data of De(carboxymethoxy) Cetirizine Acid Dihydrochloride are less reported. However, as an organic compound, it should be considered as a potentially hazardous substance. General safety practices for chemical handling should be followed during handling, such as wearing appropriate protective gloves, eye protection and laboratory clothing. In case of skin contact, inhalation or ingestion, immediately wash or seek medical treatment. When used or stored, it should be kept away from flammable materials and oxidizing agents, and properly sealed and stored.

However, due to limited information, it is recommended to refer to the relevant chemical safety data sheet for this compound for more detailed safety information. For any questions related to the use and handling of this compound, please consult a professional or relevant information to ensure safety and compliance.

Last Update：2024-04-09 22:09:11